heteroresistance

heteroresistance

(hĕt″ĕr-ō-rĭ-zĭs′tĭns) [″ + ″]
The presence within a population of a pathogen of some organisms that are susceptible to an antimicrobial drug and some that are not. Heteroresistance may explain why failure to eradicate an infection occurs in some patients treated with a seemingly appropriate antibiotic.
heteroresistant, adjective
References in periodicals archive ?
Heteroresistance to colistin in Klebsiella pneumoniae associated with alterations in the PhoPQ regulatory system.
3 Interestingly, in this study, all strains were found sensitive to colistin, whereas up to 50% heteroresistance to colistin has been reported globally.
In addition, the presence of wild-type sequence along with the corresponding mutant probe indicated the sample carrying heteroresistance isolate.
Introduction: Colistin can be used in patients infected with carbapenem-resistant Acinetobacter baumannii complex (CR-ABC), but recently resistance to colistin and heteroresistance have been reported.
13) The presence of WT along with MUT bands in RIF-resistant isolates expressed either heteroresistance or mixed infection.
Digital PCR to detect and quantify heteroresistance in drug resistant Mycobacterium tuberculosis.
Vancomycin Heteroresistance in Bloodstream Isolates of Staphylococcus capitis.
Absence of known mutations in these resistant strains might be an indication to the presence of other rare rpoB mutations heteroresistance (a mixed infection of susceptible and resistant subpopulations), or less likely another mechanism of resistance to rifampicin (BArtfai et al.
Characterization of heteroresistance to fluconazole among clinical isolates of Cryptococcus neoformans.