heteroresistance

heteroresistance

(hĕt″ĕr-ō-rĭ-zĭs′tĭns) [″ + ″]
The presence within a population of a pathogen of some organisms that are susceptible to an antimicrobial drug and some that are not. Heteroresistance may explain why failure to eradicate an infection occurs in some patients treated with a seemingly appropriate antibiotic.
heteroresistant, adjective
References in periodicals archive ?
In order to identify if the autocorrelation problem exists, the Woodridge test was used and the Wald test was used for the heteroresistance problem test.
Limits of detection (LOD) of potential heteroresistance (reflected by subpopulations of reads bearing a mutation), depending on the coverage depths over individual sequence positions, are indicated by gray (LOD 3%) and orange (variable LOD >3%-80%) above the reference sequences.
aureus isolates showed vancomycin MIC = 2 mg/L, 19 (53%) MRSA, which were then tested for vancomycin heteroresistance by screening tests.
Misidentification of Ampicillin-Sulbactam Heteroresistance In Acinetobacter baumannii Strains From ICU Patients.
Vancomycin MIC plus heteroresistance and outcome of methicillin-resistant Staphylococcus aureus bacteremia: trends over 11 Years.
Kwon-Chung, "Heteroresistance to fluconazole in Cryptococcus neoformans is intrinsic and associated with virulence," Antimicrobial Agents and Chemotherapy, vol.
Their phenotypic imipenem heteroresistance was previously characterized [11].
gattii complex have some attributes that can hinder antifungal therapy, such as heteroresistance to fluconazole [12].
Moreover, heteroresistance to colistin is a common phenomenon that is widely underestimated, requiring specific methods [30-32].
Heteroresistance to colistin in Klebsiella pneumoniae associated with alterations in the PhoPQ regulatory system.
This resistance pattern is much higher than 75.2% in Algeria and 60.9% in China,17 whereas similar results to this study (higher resistance) was reported from Pakistan Institute of Medical Sciences (PIMS) Islamabad.3 Interestingly, in this study, all strains were found sensitive to colistin, whereas up to 50% heteroresistance to colistin has been reported globally.16