heterophile antibody test


Also found in: Encyclopedia.

heterophile antibody test

A laboratory test for infectious mononucleosis.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
A heterophile antibody test was negative, however, as were EBV titers.
The diagnosis of infectious mononucleosis was based on the patient's history, physical examination, laboratory findings, serological detection, and heterophile antibody test. Combined with increased serum lipase level and radiological evidence, the diagnosis of acute pancreatitis is not difficult.
Blood cultures, monospot test (a form of the heterophile antibody test for infectious mononucleosis due to Epstein-Barr virus), and serology for hepatitis viruses were all negative.
The sharing of antigens between rickettsia and proteus is the basis of this heterophile antibody test. It demonstrates agglutinins to Proteus vulgaris strain OX 19, OX 2 and OX K.
To avoid this, serum specimens should be mixed with staphylococcal protein A to adsorb the rheumatoid factor--an unnecessary complication with the existence of the heterophile antibody test.
Children with acute infectious mononucleosis were diagnosed by symptoms, >10% atypical lymphocytes, and a positive heterophile antibody test. The PCR found a sensitivity and specificity of 75% and 98% at 1 week.
It is correct, that for the purposes of the algorithm, we have assumed that all persons with a positive heterophile antibody test had infectious mononucleosis and did not need to be routinely evaluated further virologically.
The assumption was made that a heterophile antibody test was initially requested by the patient's physician in response to presenting clinical signs and symptoms suggestive of an infectious mononucleosis-type illness.
(3) He also had the typical clinical picture, hematologic changes, and serologic response of infectious mononucleosis, ie, a young adult with sore throat, malaise, fatigue, headache, pharyngitis, abnormal liver function tests, a relative and absolute lymphocytosis with an elevated percentage of atypical lymphocytes, and a positive heterophile antibody test. (2,3)