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Related to heterophile: heterophile antigen


1. a finely granular polymorphonuclear leukocyte represented by neutrophils in human, but characterized in other mammals by granules that have variable sizes and staining characteristics.
2. heterophilic (def. 1).
heterophil antibody a characteristic antibody found with infectious mononucleosis, demonstrated in 90 to 95 per cent of adolescents and adults and 50 per cent of children with the disease. It declines in titer after acute illness has resolved but may be detectable for up to 9 months after disease onset.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


, heterophile (het'ĕr-ō-fil, -fīl),
1. Pertaining to heterogenetic or cross-reacting antigens occurring in different species or to antibodies directed against such antigens.
2. The neutrophilic leukocyte in humans; in some animals, the granules vary in size and staining reaction.
[hetero- + G. philos, fond]
Farlex Partner Medical Dictionary © Farlex 2012


, heterophile (het'ĕr-ō-fil, -fīl)
1. The neutrophilic leukocyte.
2. Pertaining to heterogenetic antigens occurring in different species or to antibodies directed against such antigens.
[hetero- + G. philos, fond]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
The combination of a patient having greater than 50% lymphocytes and greater than 10% atypical lymphocytes is also useful.[sup][2] However, the Hoagland criteria state that in patients presenting with clinically suspected infectious mononucleosis, the diagnosis should be confirmed using the heterophile antibody (monospot) test.
A monospot test was positive for the presence of heterophile antibodies and further serological testing was carried out which detected the presence of IgM and IgG antibodies to the Epstein-Barr viral capsid antigen (VCA).
Investigation of primary human immunodeficiency virus infection in patients who test positive for heterophile antibody.
Serum levels of immunoglobulins, heterophile antibodies, and antibodies to T.
But it has the disadvantage that the test sera need to be absorbed free from heterophile antibody.
The sharing of antigens between rickettsia and proteus is the basis of this heterophile antibody test.
The ghost in the assay tube: heterophile antibody interferences in immunoassays - an ever-recurring but often forgotten problem.
ELISA-VIDITEST and IF-VIDITEST anti-HHV-6 kits are intended for serological diagnosis of diseases associated with HHV-6 infection, such as exanthema subitum, acute respiratory illnesses, diarrhoea with fever and febrile seizures in infants, heterophile antibody-negative infectious mononucleosis in children, also interstitial pneumonia, encephalitis, meningitis, hepatitis, and aplastic anemia in immunodeficient patients.
Phantoms in the assay tube: heterophile antibody interferences in serum thyroglobulin Assays.
Following a positive heterophile antibody test for Epstein-Barr virus, he was diagnosed with mononucleosis.