heteroduplex

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het·er·o·du·plex

(het'ĕr-ō-dū'pleks),

1. A DNA molecule, the two constitutive strands of which derive from distinct sources and hence are likely to be somewhat mismatched.

2. A DNA-RNA hybrid.

[hetero- + L. duplex, two-fold]

Farlex Partner Medical Dictionary © Farlex 2012

het·er·o·du·plex

(het'ĕr-ō-dū'pleks)

1. A DNA molecule, the two constitutive strands of which derive from distinct sources and hence are likely to be somewhat mismatched.

2. A DNA-RNA hybrid.

[hetero- + L. duplex, two-fold]

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

heteroduplex

a DUPLEX DNA in which the two strands do not show COMPLEMENTARY BASE PAIRING throughout, but instead contain one or more MISMATCHES OF BASES. A heteroduplex may be formed during RECOMBINATION, for example. Compare HOMODUPLEX.

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

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References in periodicals archive ?

The PAM sequence readout by Arg1333 and Arg1335 of Cas9 facilitates the interaction of +1 phosphate group with the phosphate lock loop that promotes the melting of the local DNA, and gRNA-target DNA heteroduplex formation in a directional manner [64].

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However, better results with faster rates may not apply to other melting applications that use larger amplicons >100 bp such as heteroduplex scanning.

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Heteroduplex Panel Analysis, a Novel Method for Genetic Identification of Aspergillus Section Flavi Strains.

Identification of Single-Base Mismatches in Pneumocystis jirovecii Isolated from Iranian TB positive Patients by CSGE Heteroduplex

In this approach, CEL1 cleaves at the site of heteroduplex indicating mismatches in the sequences.

Allelic variation of wheat flour allergens in a collection of wheat genotypes

Heteroduplex molecules cause sexing errors in a standard molecular protocol for avian sexing.

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The HRM method depends on heteroduplex formation; therefore, statistically rare homozygous mutations with DNA binding affinity equal to that of wild type might not be detected.

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lindheimeri, 4 fragments, 202 base-pair heteroduplex fragment, 187 base pair fragment from parent of D.

Concordance between molecular and morphological evidence of hybridization in the Dichanthelium acuminatum (Poaceae: Paniceae) subspecies complex

Heteroduplex molecules formed between allelic sequences cause nonparental RAPD bands.

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The results of the dHPLC showed several heteroduplex peaks on the chromatograms of samples (Figure 1).

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These extra bands are heteroduplex DNA molecules formed after denaturation and reannealing of species-specific PCR products (i.e., they are not formed in unheated but Hae III-digested mixtures of species-specific PCR products; Fig.

The Kumamoto oyster Crassostrea sikamea is neither rare nor threatened by hybridization in the Northern Ariake sea, Japan

Effect of PCR conditions on the formation of heteroduplex and single-stranded DNA products in the amplification of bacterial ribosomal DNA spacer regions.

A posit1ve control for detecting heteroduplexes in DGGE for microbial community fingerprinting