heterodimer


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Related to heterodimer: Homodimer, Heterodimerize

het·er·o·di·mer

(het'ĕr-ō-dī'mĕr),
A molecule composed of paired proteins with some amino-acid sequence variations.
[hetero- + dimer]
References in periodicals archive ?
0,+]-like amino acid transporter functioning as a heterodimer with 4F2hc instead of rBAT.
HER2 has the strongest catalytic kinase activity and HER2-containing heterodimers have the strongest signaling activity.
Expression of the classical class II heterodimers on cattle leucocytes was identified using cross-species-reactive monoclonal antibodies (mAb) (Lewin et al.
These receptors share a highly conserved DNA-binding domain and a discrete ligand-binding domain, and bind to hormone response elements (HREs) on the DNA during the formation of homodimers, heterodimers, or monomers.
Heterodimers of [alpha]- and [gamma]-enolases have been observed in rat brain synaptic terminals (Ueta et al.
Presentation of scientific data on the HER1 and HER3 total protein assays, the HER1:HER1 homodimer assay, the HER1:HER2 and HER2:HER3 heterodimer assays and the PI3K assay (at the 20th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Geneva, Switzerland in October 2008, at the AACR "Targeting the PI3-Kinase Pathway in Cancer" meeting in Cambridge, MA in November 2008, and at the San Antonio Breast Cancer Symposium in December, 2008).
The data presented this week, on the HER1 and HER3 total protein assays, the HER1:HER1 homodimer assay and the activated HER1:HER2 heterodimer assay, provide support for the use of these assays in drug development programs not only in breast cancer, our current focus, but also in other cancer types.
Electron transfer flavoprotein exists in the mitochondrial matrix and has two heterodimer forms, involving 30 and 28 kDa subunits, and one flavin adenine dinucleotide (FAD) and one adenosine 5'-monophosphate (AMP).
To investigate whether ApoA5 might circulate as a disulfide-linked homodimer or heterodimer, we immunoprecipitated the protein from 100 [micro]L of pooled human serum added to 1 mL of lysis buffer in 1.
The FSH assay, based on heat dissociation of the FSH heterodimer and measurement of the FSH [beta]-subunit (Qiu et al.
The 97-kDa MTP and 55-kDa protein disulfide isomerase form a heterodimer that acts as a chaperone as well as facilitating lipid transfer from the ER membrane to nascent apoB (16).
We have also reported data on three of our new assays - those for HER3, for the HER2:HER3 heterodimer and for the HER3:PI3K complex.