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"If you account for the fact that most West Nile cases are concentrated in the summer months and in certain geographic areas, whereas herpes of course is year-round and not with any geographic predilection, in some of those areas the relative incidence of West Nile encephalitis over
herpes simplex encephalitis is actually quite large," according to Dr.
Unlike in
herpes simplex encephalitis, where well over 90% of biopsy-proven affected patients display intracranial neuroimaging abnormalities, that's true for only about half of patients with WNV encephalitis, and even then special MRI techniques such as flare or fast-spin often are required.