hereditary thrombophilia

hereditary thrombophilia

(1) Antithrombin III deficiency. 
(2) Protein C deficiency.

hereditary thrombophilia

Hematology A hereditary ↑ tendency to form intravascular blood clots Etiology Factor V Leiden, prothrombin G20210A polymorphism, defects in homocysteine metabolism, protein C, protein S or antithrombin III. See LETS.
References in periodicals archive ?
Do not order MTHFR genetic testing for the risk assessment of hereditary thrombophilia.
Testing for hereditary thrombophilia in patients following a first episode of intra-abdominal thrombosis or cerebral sinus thrombosis does not clearly predict the risk of recurrence, and it does not provide evidence-based data on which to determine the duration of treatment.
2) Causes for hereditary thrombophilia result from single gene mutations, and include protein C deficiency, protein S deficiency, antithrombin deficiency, prothrombin mutation, and factor V Leiden.
The prevalence of this hereditary thrombophilia depends on the patient population: It is more common in whites than in African Americans, and it is almost never found in Asian or Hispanic patients.
Hereditary thrombophilia is detected in more than half of the patients in whom thrombophilic defects are present.
24) performed a case-control study of 219 hospital cases with a first-ever IS and 205 randomly selected community control subjects in order to identify the role of hereditary thrombophilia in IS.
Two forms of hereditary thrombophilia increase procoagulant activity.
Having more than one cause of hereditary thrombophilia substantially increases the associated VTE risk.
WASHINGTON, April 30 /PRNewswire/ -- Enoxaparin, an anticoagulant, has proven to be an effective preventive measure against stillbirth in pregnant women with hereditary thrombophilia, according to a new study published in the May 15, 2004, issue of Blood, the official journal of the American Society of Hematology.
Defects within the protein C system can be detected in 25-50% of hereditary thrombophilia [1].
Because our patient had thrombosis attacks in the upper and lower extremities, although he was thrombocytopenic when the first attack occurred, we investigated hereditary thrombophilia and found three hereditary thrombophilic risk factors.

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