hereditary spastic paraplegia


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hereditary spastic paraplegia

Any of a group of inherited diseases of the central nervous system characterized by muscle spasticity, esp. of the lower extremities.
Synonym: Troyer syndrome
See also: paraplegia
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Hereditary spastic paraplegia (HSP) includes a large and diverse group of genetic disorders whose main feature is progressive spasticity and weakness in the lower limbs, as a result of continuous distal axonopathy caused by defects in the mechanisms that transport proteins and substances along the axons [90, 91].
Fink, "Hereditary spastic paraplegia: clinico-pathologic features and emerging molecular mechanisms," Acta Neuropathologica, vol.
FSP is also called hereditary spastic paraplegia and StrA1/4mpell-Lorrain syndrome1.

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