hereditary spastic paraplegia


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hereditary spastic paraplegia

Any of a group of inherited diseases of the central nervous system characterized by muscle spasticity, esp. of the lower extremities.
Synonym: Troyer syndrome
See also: paraplegia
References in periodicals archive ?
Hereditary spastic paraplegia Emery and Rimoin's principles and practice of medical genetics.
Valdez: on the way to victory in the Hereditary Spastic Paraplegia Awareness Novices' Hurdle at Huntingdon in November
Accumulated evidence indicates that oxidative stress plays a major role in the pathogenesis of several neurodegenerative diseases, including Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), multiple sclerosis (MS), and hereditary spastic paraplegia (HSP).
There was just a thought she may say no but I'm delighted she didn't", said Roo, who suffers from what is known as Spordadic Hereditary Spastic Paraplegia.
Many mutations for the motor axon degeneration disease, hereditary spastic paraplegia (HSP), affect proteins that model ER shape.

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