hereditary diffuse gastric cancer


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hereditary diffuse gastric cancer

An autosomal dominant cancer predisposition syndrome (OMIM:137215) with increased susceptibility to diffuse cancer, which begins in the stomach and typically spreads locally to the oesophagus, small intestine and other organs, as well as to adjacent lymph nodes.
 
Molecular pathology
CDH1 mutation causes hereditary diffuse gastric cancer.
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