genetic disorder

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genetic disorder

A pathological condition caused by an absent or defective gene or by a chromosomal aberration. Also called hereditary disease.

genetic disorder

ge·net·ic dis·or·der

(jĕ-net'ik dis-ōr'dĕr)
A widely used but nonetheless imprecise term that denotes a condition or illness related to biologic inheritance.

Patient discussion about genetic disorder

Q. what makes Arthritis a genetic disease?

A. First of all, the term arthritis is a bit inaccurate: Arthritis denotes an inflammation of joints. There are many kinds of arthritis that may result from different causes, and therefore, are different diseases: septic arthritis (inflammation due to infection of joint) has much less genetic background than ankylosing spondylitis (an arthritis of the lower back joints that occurs almost exclusively in people with certain genetic background).

The arthritis with the genetic background are usually the autoimmune ones: Due to genetic determinants, the immune system of some people is programmed to recognize the various parts of the joints (and other organs as well) as foreign (i.e. like bacteria) and thus launches an attack on them. In normal immune system, that doesn't happen.

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Q. Is bipolar disease a hereditary problem? My only son is in his teens that is the age to enjoy life, but he cannot enjoy his life with his friends because we found that he is suffering from a bipolar condition. I feel so sad for him and though my care-free days have gone, I often think about how much fun I had at his age. I too suffered from a bipolar disorder and my mom too. Is bipolar disease a hereditary problem? I want him to help to enjoy his life.

A. I agree with you. No one should suffer because of hereditary problems. This is the same situation here as genes are passed from generation to generation. This information is inconclusive because many who may have had bipolar disorders did not have it checked out. Who is to say, how many people 50 years ago had it but dismissed it as being moody, or ill tempered. Doctors were not aware about this problem years ago. Some time back, someone who showed signs of a mental disorder was straight away shoved into a mental hospital and left to suffer. Besides they are often treated with electric shock therapy eventually getting out of control. Testing is still in progress to find out if genetics play a role but these theories may take several more years before they can have a better understanding.

Q. Is FMS heredetery? My mother was diagnosed with FMS and I would like to know what are the chances I’ll have it too.

A. Hereditary is not the right term. It’s not a genetic disease but The cause of fibromyalgia remains elusive. However, recent studies show that genetic factors can predispose individuals to a genetic susceptibility to fibromyalgia.

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References in periodicals archive ?
Scientists carried out a genome-wide linkage study in a US family with an unusual hereditary condition affecting 24 members of the family over five generations.
Nanna has been diagnosed with luxating patellas, an uncommon hereditary condition in cats in which the patella (knee cap) moves in an abnormal position.
The faulty gene was the one responsible for haemophilia, meaning that the process cured the mouse of the hereditary condition, which can be life-threatening in humans.
It means that parents with the hereditary condition may be able to predict more accurately the chances of passing it on to their children.
Al l three have the deadly hereditary condition sickle cell anaemia.
Since then, Mark's mum Yvonne has found out she has the same hereditary condition after suffering palpitations and other symptoms similar to the ones her son complained about.
The tumour started in his lower lip, and spread to his lower jaw - a rare and complex hereditary condition that required a maxillofacial surgery (free flap surgery).
The eight-month-old girl, who lives in Saltley, Birmingham, suffers from a rare bone disorder called malignant infantile osteopetrosis, which is a hereditary condition that affects one in 500,000 babies.
They also stop us falling down bunkers," laughs Mike, who suffers from retinal degeneration - a hereditary condition which means that although he can't always see what's right in front of him, he does have some peripheral vision around the sides.
However, Henderson's career was almost short-circuited when she experienced hearing loss--resulting from a hereditary condition called osteosclerosis--during a stint in The King and I.
Shop worker Toni was diagnosed with lupus, a hereditary condition which causes the immune system to attack body, at 17.
Rita Buchan decided to screen the rest of her family after son Jamie, 29, died of the often hereditary condition, cardiomyopathy, when riding his bicycle.

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