hereditary angioedema
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angioedema
[an″je-o-ĕ-de´mah]a localized edematous reaction of the deep dermis or subcutaneous or submucosal tissues appearing as giant wheals; urticaria is the same physiologic reaction occurring in the superficial portions of the dermis.
hereditary angioedema an autosomal dominant disorder of the complement system manifested as recurrent episodes of edema of the skin, upper respiratory tract, and gastrointestinal tract. It may be mediated by such factors as minor trauma, sudden changes in environmental temperature, and sudden emotional stress. adj., adj angioede´matous.
he·red·i·tar·y an·gi·o·e·de·ma
an inherited, autosomal-dominant disease characterized by episodic appearance of brawny nonpitting edema, most often affecting the limbs, but capable of involving other parts of the body, including mucosal surfaces such as those of the intestine (causing abdominal pain) or respiratory tract (causing asphyxia, which can require intubation to avoid fatal outcome). Associated with deficiency of inhibitor of first component of complement pathway (C1). Epinephrine is used in emergency treatment, long-term treatment with a variety of agents is effective.
hereditary angioedema
n.
A hereditary disorder characterized by recurrent episodes of subcutaneous and submucosal swelling, especially affecting the limbs, face, upper respiratory tract, and gastrointestinal tract.
hereditary angioedema
an inherited autosomal-dominant disorder characterized by the episodic appearance of nonpitting edema involving any part of the body, including mucosal surfaces. The attacks last 48 to 72 hours and can be life-threatening if edema obstructs the airway.
Hereditary angioedema
A complement deficiency characterized by lymphatic vessel blockages that cause temporary swelling (edema) of areas of the skin, mucous membranes, and, sometimes, internal organs.
Mentioned in: Complement Deficiencies
he·red·i·tar·y an·gi·o·e·de·ma
(hĕr-edi-tar-ē anjē-ō-ĕ-dēmă)Inherited disease characterized by episodic appearance of brawny nonpitting edema, most often affecting the limbs, but capable of involving other body parts, including mucosal surfaces of the intestine or respiratory tract.
angioedema
a condition characterized by the sudden and temporary appearance of large areas of painless swelling in the subcutaneous tissue or submucosa, with or without pruritus. Caused by immunological reactions, usually immediate type hypersensitivities. Sometimes referred to as angioneurotic edema.
hereditary angioedema
in humans, the periodic occurrence of angioedema caused by a deficiency of the complement regulatory protein.