Toxicity of microcystin LR, a cyclic heptapeptide
hepatotoxin from Microcystis aeruginosa, to rats and mice.
Comments: RerfectionPeptide P7 is a new biologically active heptapeptide
that stimulates the skin's own self-defense mechanisms against oxidative stress.
Bremelanotide is a novel cyclic heptapeptide
that acts as a melanocortin-receptor-4 agonist.
The passenger domains of these proteins vary in the number of binding domains (hemagglutinin and Hep_Hag domains) and in possession of different-sized, low-complexity spacer regions consisting of approximate heptapeptide
Detection of colonic dysplasia in vivo using a targeted heptapeptide
and confocal microendoscopy.
The substance P (SP) heptapeptide
fragment SP1-7 alters the density of dopamine receptors in rat brain mesocorticolimbic structures during morphine withdrawal.
Studies using nerve cells suggest that one of these substances, called Heptapeptide
1, is the main agent responsible for triggering pain.
A fluorescein-labeled heptapeptide
(LeuArgArgAlaSerLeuGly) was used as substrate for the enzymatic reaction.
One enzyme, which the researchers called microcystinase, breaks the bond between two of the seven amino acids in the cyclic heptapeptide
Three trials were conducted involving the agent eptifibatide, a synthetic cyclic heptapeptide
that competitively binds to the arginine-glycine-aspartate recognition site.
These data suggest that the abalone attractin is larger, but likely contains conserved regions, similar to the second alpha helix that encompasses the heptapeptide
BACKGROUND: Microcystin-LR, a cyclic heptapeptide
, possesses the ability to inhibit the serine/threonine protein phosphatases PP1 and PP2A and, consequently, exhibits acute hepatocytotoxicity.