The doctor concluded that a gene called hepsin was the "ringleader" that allowed cancer cells to spread to others parts of the body.
That means providers don't have to buy anything but hepsin antibodies, and selling those is what Stage I does.
Actualmente, se estan estudiando los siguientes marcadores presentes en la orina: peptidasa-2 relacionada con la calicreina (KLK2); el antigeno prostatico incipiente (EPCA); el antigeno prostatico 3 (PCA3); el hepsin
o antigeno prostatico de las celulas madre y la alpha-methylacyl-CoA (AMACR).
64 ng/L, and we observed no cross-reactivity or interference with atrial natriuretic peptide (ANP), enterokinase, human airway trypsinlike protease, hepsin
, LDL receptor, matriptase, spinesin, or seipins.
These antibodies complement Signet's current product portfolio which includes markers such as D2-40, Cyclin D1, Cyclin E, HE4, and Hepsin
Lee's paper was titled "The Role of Hepsin
in an in vivo c-Myc Model of Prostate Cancer.
The protein expression of two genes, hepsin
and pim-1, was further analyzed in more than 700 clinically stratified prostate cancer specimens.
He and his collaborators have characterized a number of biomarkers of prostate cancer including AMACR, EZH2 and hepsin
Also included were prostate-cancer-specific genes such as hepsin
(HPN) and prostate-specific gene with homology to G protein receptor (PSGR), as well as therapy-relevant genes such as androgen receptor (AR), HER-2, BCL-2, multidrug resistance gene (MDR1), and epidermal growth factor receptor (EGFR).
25) used comparable technologies to confirm overexpression of hepsin
and PlM-1 in prostate cancer (Fig.