HPN

(redirected from hepsin)

HPN

A gene on chromosome 19q11-q13.2 that encodes a type-II transmembrane serine protease involved in cellular functions, including coagulation, maintenance of cell morphology and growth and progression of certain cancers (e.g., of the prostate).

Home parenteral nutrition (HPN)

Long-term parenteral nutrition, given through a central venous catheter and administered in the patient's home.
References in periodicals archive ?
The doctor concluded that a gene called hepsin was the "ringleader" that allowed cancer cells to spread to others parts of the body.
That means providers don't have to buy anything but hepsin antibodies, and selling those is what Stage I does.
Actualmente, se estan estudiando los siguientes marcadores presentes en la orina: peptidasa-2 relacionada con la calicreina (KLK2); el antigeno prostatico incipiente (EPCA); el antigeno prostatico 3 (PCA3); el hepsin o antigeno prostatico de las celulas madre y la alpha-methylacyl-CoA (AMACR).
64 ng/L, and we observed no cross-reactivity or interference with atrial natriuretic peptide (ANP), enterokinase, human airway trypsinlike protease, hepsin, LDL receptor, matriptase, spinesin, or seipins.
These antibodies complement Signet's current product portfolio which includes markers such as D2-40, Cyclin D1, Cyclin E, HE4, and Hepsin.
Lee's paper was titled "The Role of Hepsin in an in vivo c-Myc Model of Prostate Cancer.
The protein expression of two genes, hepsin and pim-1, was further analyzed in more than 700 clinically stratified prostate cancer specimens.
He and his collaborators have characterized a number of biomarkers of prostate cancer including AMACR, EZH2 and hepsin.
Also included were prostate-cancer-specific genes such as hepsin (HPN) and prostate-specific gene with homology to G protein receptor (PSGR), as well as therapy-relevant genes such as androgen receptor (AR), HER-2, BCL-2, multidrug resistance gene (MDR1), and epidermal growth factor receptor (EGFR).
25) used comparable technologies to confirm overexpression of hepsin and PlM-1 in prostate cancer (Fig.