hepatorenal syndrome


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Related to hepatorenal syndrome: Hepatopulmonary syndrome

hepatorenal

 [hep″ah-to-re´nal]
pertaining to the liver and kidneys.
hepatorenal syndrome oliguria and renal failure in a patient with anatomically and morphologically normal kidneys in the presence of liver failure. Prognosis is poor.

hep·a·to·re·nal syn·drome

, hepatonephric syndrome
the occurrence of acute renal failure in people with disease of the liver or biliary tract, apparently due to decreased renal blood flow and conditions that damage both organs, such as carbon tetrachloride poisoning and leptospirosis.

hepatorenal syndrome

n.
A condition in which acute renal failure occurs with disease of the liver or biliary tract.

hepatorenal syndrome

a type of kidney failure characterized by a gradual loss of function without signs of tissue damage. It is associated with hepatitis or cirrhosis of the liver; its exact cause is unknown.

hepatorenal syndrome

Bile nephrosis Hepatology A complication of liver failure characterized by acute renal dysfunction without renal pathology, due to ↓ perfusion, hypovolemia, and hyperaldosteronism, 2º to liver disease–eg, cirrhosis, acute fatty liver, hepatic failure, obstructive jaundice, sepsis, infectious hepatitis Etiology Unclear Clinical ↓/absent urine, jaundice, bloating, delirium, confusion, N&V Prognosis Very poor;13 relentlessly deteriorate. Cf Cirrhotic glomerulonephritis.

hep·a·to·re·nal syn·drome

, hepatonephric syndrome (hep'ă-tō-rē'năl sin'drōm, hĕp'ă-tō-nĕf'rik)
The occurrence of acute renal failure in patients with disease of the liver or biliary tract.

hepatorenal syndrome

A form of kidney failure occurring in CIRRHOSIS of the liver, not because of kidney disease but probably because of greatly diminished blood flow through the kidneys because of renal vasoconstriction. The outlook is very poor unless liver transplantation is performed.
References in periodicals archive ?
Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis.
Improvement of hepatorenal syndrome with extracorporeal albumin dialysis MARS: Results of a prospective, randomized, controlled clinical trial.
PTX also decreased the percentage of deaths caused by hepatorenal syndrome.
A review of the Hepatorenal Syndrome products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
2) Serious complications from cirrhosis, which may contribute to hospitalization and even death, include variceal bleeding, spontaneous bacterial peritonitis, hepatocellular carcinoma, hepatorenal syndrome, hepatic encephalopathy, and hepatopulmonary syndrome.
Williams first used MARS 2 years ago in a patient with severe acute alcoholic hepatitis and hepatorenal syndrome, a condition with high mortality.
Cases of hepatic failure, hepatorenal syndrome, acute renal failure (all including fatalities), and renal insufficiency have been reported during use of Tarceva.
Cases of hepatic failure, hepatorenal syndrome, acute renal failure (all including fatalities) and renal insufficiency have been reported during use of Tarceva.
Cumberland completed enrollment in the first of two patient cohorts of its Phase II study of Hepatoren in patients with Hepatorenal Syndrome (HRS).
Cumberland is also currently studying ifetroban in an injectable formulation in a Phase II study in patients with Hepatorenal Syndrome (HRS), a life-threatening condition involving progressive kidney failure.
Clinical deterioration, manifested by new onset or worsening encephalopathy, ascites, or hepatorenal syndrome, was reported in patients with Child-Pugh B or C cirrhosis who received single-agent CYRAMZA.
The company's main product candidates include GCS-100 for the treatment of chronic kidney disease (CKD), LJPC-501 that is designed to help restore kidney function in patients with hepatorenal syndrome (HRS), and LJPC-401 for the treatment of iron disorders.