hepatoma


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hepatoma

 [hep″ah-to´mah]
1. a tumor of the liver.

hepatocellular carcinoma (HCC),

[MIM*114550]
Malignant tumor of the liver that develops in the setting of chronic liver disease or cirrhosis. Hepatocellular carcinoma is derived from hepatocytes that are transformed into adenocarcinoma. Up to 60% of patients with HCC have elevated serum alpha fetoprotein levels. Tumor has a poor long-term prognosis unless treated surgically by resection or liver transplantation. Noninvasive imaging (e.g., MRI or CT scan) may distinguish hepatomas from other benign tumors such as hemangiomas.

hepatoma

(hĕp′ə-tō′mə)
n. pl. hepato·mas or hepato·mata (-mə-tə)
A usually malignant tumor occurring in the liver.

hepatoma

(1) Hepatocellular carcinoma; liver cell carcinoma.
(2) Liver cell adenoma.

hepatoma

Hepatocellular carcinoma, see there.

ma·lig·nant hep·a·to·ma

(mă-lig'nănt hep'ă-tō'mă)
A carcinoma derived from parenchymal cells of the liver.
Synonym(s): hepatocarcinoma, hepatocellular carcinoma.

hepatoma

A primary cancer of the liver (hepatocellular carcinoma). Primary liver cancer is rare in the Western world while secondary cancer is very common. Hepatomas are common in areas in which exposure to HEPATITIS B and AFLATOXINS occur frequently. In these areas, males with CIRRHOSIS are especially prone. There are high blood levels of ALPHAFETOPROTEIN. Surgery is sometimes feasible but the outlook is poor.
References in periodicals archive ?
Infection of a human hepatoma cell line by hepatitis B virus.
Berberine induces cell death in human hepatoma cells in vitro by downregulating CD147.
This led us to observe that the expression of Enpp1 in rat primary hepatocytes and human hepatoma cells is regulated by insulin and glucocorticoid.
Zhang, "Molecular mechanism of HEIH and HULC in the proliferation and invasion of hepatoma cells," International Journal of Clinical and Experimental Medicine, vol.
Hepatoma HepG2 cells (200,000 cells/well of 12-well plates) were pretreated with DMSO (vehicle, 0.1% v/v) or EPA and/or DHA (10, 25, or 50 [micro]M) for 3, 6, 16, or 24 H and then cultured for up to 24 H in the presence of a BA mixture (CDCA, CA, DCA, and LCA, 100 [micro]M each).
This work proposes an intelligent medical decision support system for the classification of hepatobiliary disorders including alcoholic liver damage, primary hepatoma, liver cirrhosis, and cholelithiasis.
Zhang et al., "The therapeutic effect of PEI-[Mn.sub.0.5][Zn.sub.0.5][Fe.sub.2][O.sub.4] nanoparticles/pEgr1-HSV- TK/GCV associated with radiation and magnet-induced heating on hepatoma," Nanoscale, vol.
Table 1: Cytodiagnosis profile of liver SOL (n=340) Types of lesions Number of cases (%) Neoplastic lesions Hepatocellular carcinoma 82 (24.11) Hepatoblastoma 08 (2.35) Metastatic carcinoma 226 (66.47) Total 316 (92.94) Nonneoplastic lesions Liver abscess 15 (4.41) Hydatid cyst 06 (1.76) Hemangioma 03 (0.88) Total 24 (7.06) Table 2: Clinical presentation of six cases of HD Age (years) Symptoms Diameter of USG diagnosis SOL (in cm) 39 Nil 5.0 Hepatoma 60 Nil 2.5 HD 52 Nil 5.2 Hepatoma 29 Abdominal pain 1.5 HD 39 Nil 5.0 Hepatoma 49 Abdominal pain 3.8 Hepatoma SOL: Space occupying lesion, HD: Hydatid disease, USG: Ultrasonography
This reduces the liver fibrosis and chances of development of hepatoma.5, 11
Morris hepatoma 3942A (CLS Cell lines service GmbH), which is similar to human hepatocellular carcinoma, was implanted in August Copenhagen Irish rats (ACI, Harlan Sprague Dawley Inc.) in this study.
The human hepatoma cell line HepG2 was purchased from American Type Culture Collection (Manassas, VA).
It has been reported that curcumin and related analogous compounds could induce apoptosis in hepatoma cells that express p53 protein normally (e.g., HepG2 cell) through p53/p21 pathway [14-16].