carcinoma of the ovary (HCO) is a rare tumor of uncertain histogenesis that affects mostly peri- and postmenopausal women.
Rare, and infrequently reported variants of EC include hepatoid
carcinoma, glassy cell carcinoma, lymphoepithelioma-like carcinoma, adenocarcinoma with trophoblastic differentiation, and giant cell carcinoma (GCC) (3).
cells were seen in adenomas and clusters of variable sized neoplastic cells with anisokaryosis, coarse chromatin with one or two nucleoli and basophilic cytoplasm in adenocarcinoma, which was correlated with the finding of Tyler et al.
(2010) SALL4 represents fetal gut differentiation of gastric cancer, and is diagnostically useful in distinguishing hepatoid
gastric carcinoma from hepatocellular carcinoma.
In particular, it has been reported that HER2 overexpression rate progressively increases moving from the poorly cohesive WHO histotype to the mitochondrion-rich adenocarcinoma (MRC), tubular adenocarcinoma, and hepatoid
carcinoma (HAS), which showed the highest frequency of HER2 positivity and the worst prognosis .
A gastrointestinal scope after TACE and HAIC showed a Borrmann type 2 lesion on the pyloric portion of the lesser curvature, which was histologically diagnosed as suspected hepatoid
adenocarcinoma (Figure 4).
No CA component, hepatoid
carcinoma, yolk sac tumor, or other histological cell types were found in any section.
Notably, compared with the serum AFP < 20 ng/ml group, 10 (13.5%) patients were diagnosed with hepatoid
adenocarcinoma in the AFP [greater than or equal to] 20 ng/ml group.
adenocarcinoma arising from heterotopic pancreas of the ileum: a case report," Medicine, vol.
Primary adenocarcinoma of the urinary bladder is a rare malignancy, characterized by a wide range of histological varieties, such as colonic type, mucinous type, signet-ring cell type, clear cell type, hepatoid
, and adenocarcinoma not otherwise specified .
Histopathology diagnoses were squamous cell carcinoma (three cases), basal cell carcinoma, perianal mucinous adenocarcinoma, hepatoid
carcinoma, and apocrine carcinoma with squamous differentiation.
These cells were hepatoid
in appearance, with distinct cell borders and abundant, deeply eosinophilic to basophilic, finely granular cytoplasm.