hepatocyte growth factor


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hepatocyte growth factor

A cytokine monokine involved in immune and inflammatory responses. It is produced by platelets, fibroblasts, macrophages, endothelial cells, and smooth muscle cells. It stimulates growth of hepatocytes and increases migration and motility of various epithelial and endothelial cells.
See also: factor
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Nakamura, "Emerging multipotent aspects of hepatocyte growth factor," Journal of Biochemistry, vol.
Kim, "Role of the spleen in liver regeneration in relation to transforming growth factor-[beta]1 and hepatocyte growth factor," Journal of Surgical Research, vol.
Clavijo-Cornejo et al., "Hepatocyte growth factor protects against isoniazid/ rifampicin-induced oxidative liver damage," Toxicological Sciences, vol.
* The report reviews Hepatocyte Growth Factor (Hepatopoietin-A or Lung Fibroblast Derived Mitogen) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
Supplementary immunocytochemistry of hepatocyte growth factor production in activated macrophages early in muscle regeneration.
Hepatocyte growth factor effects on mesenchymal stem cells: proliferation, migration, and differentiation.
"We are hoping that the treatment will increase the local production of hepatocyte growth factor to help regenerate nerves and grow new blood vessels and therefore reduce the pain," explains coauthor Senda Ajroud-Driss, associate professor in neurology and an attending physician at Northwestern Memorial Hospital.
Angiogenesis induced by hepatocyte growth factor in non-infarcted myocardium and infarcted myocardium: up-regulation of essential transcription factor for angiogenesis, ets.
Schmidt, "Hepatocyte growth factor in transgenic mice: effects on hepatocyte growth, liver regeneration and gene expression," Hepatology, vol.
Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats.
[sup.99m]Tc-GSA scintigraphy to detect uptake ratio of the heart at 15 minutes to that at three minutes ([HH.sub.15]) and uptake ratio of the liver at 15 minutes to the liver plus the heart at 15 minutes ([LHL.sub.15]), and measurements of serum total bilirubin, hepatocyte growth factor and prothrombin time were performed immediately after the diagnosis of acute liver failure.
Hepatocyte growth factor (HGF; also known as scatter factor) is the only known c-Met ligand.

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