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Neuroendocrine-regulating genes are found in all three types of tumors [9]; this genomic print suggests that these tumors may have a different origin than that of hepatocarcinomas, which could produce directed treatments in the future [10].
Similarly, the NMs may also cause damage to liver cells during cleansing of toxins and pollutants in body Furthermore, the Ti[O.sub.2] NPs may cause hepatotoxicity in human hepatocellular carcinoma cell line (SMMC-7721), human liver cell line (HL-7702), rat hepatocarcinoma cell line (CBRH-7919), and rat liver cell line (BRL-3A), which may be associated with changes in cell morphology, increased intercellular ROS production, and decreased GSH levels at 0.1-100 [micro]g/mL [13].
In brief, these results proved that FA-PEG-MSNs-PTX was a new drug nanocarrier for the efficient delivery of PTX to hepatocarcinoma cells, especially for applications involving liver cancer chemotherapy.
HepG2 (human hepatocarcinoma cells) and 3T3-L1 (mouse embryonic fibroblasts) cell lines were purchased from Korean Cell Line Bank (Seoul, Korea).
Giovannini et al., "MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells," Cancer Research, vol.
Shen, "Study of combined treatment with traditional Chinese medicine for advanced primary hepatocarcinoma," Chinese Journal of Clinical Oncology and Rehabilitation, vol.
The selectivity index was determined as the ratio of [IC.sub.50] value of normal AML12 hepatocytes to that of hepatocarcinoma HepG2 cells.
Rutin inhibits oleic acid induced lipid accumulation via reducing lipogenesis and oxidative stress in hepatocarcinoma cells.
It is typically expressed by normal epithelial cells and B-cells, but it was shown to function as a TAA in hepatocarcinoma and cervical cancer [10,14,15].
(23) compared 94 patients with CHC, cirrhosis of the liver or primary hepatocarcinoma with a 31 -member healthy control group and reported higher serum TNF alpha levels in the three patient groups than in the control group.
Similar results have been reported in prostate, (28) breast, (29) and hepatocarcinoma cancer (30) cell lines.
Anti-metastasis effect of fucoidan from Undaria pinnatifida sporophylls in mouse hepatocarcinoma Hca-F cells.

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