hepatitis C virus genotype

hepatitis C virus genotype

genetic heterogeneity and divergence in the viral sequences produce at least six genotypes of HCV. Genotypes cluster geographically (e.g., genotypes 1a and 1b typically found in the United States and Europe, genotype 4 in Africa and the Middle East, genotypes 5 and 6 in Southeast Asia and South Africa). Response to interferon therapy depends on HCV genotype.
References in periodicals archive ?
Interferon sensitivity-determining region of nonstructural region 5A of hepatitis C virus genotype 1b correlates with serum alanine aminotransferase levels in chronic infection.
Hepatitis C virus genotype distribution in Egyptian diabetic patients: a preliminary study.
The POLARIS-1 study has evaluated Vosevi for 12 weeks in adults with hepatitis C virus genotype 1, 2, 3, 4, 5 or 6 with or without compensated cirrhosis who had failed prior treatment with an NS5A inhibitor-containing regimen.
Effect of interferon plus ribavirin therapy on hepatitis C virus genotype 3 patients from Pakistan: treatment response, side effects and future prospective.
4 In Indonesia, a study in several hospitals of Jakarta, reported that hepatitis C virus genotype 1 is the most prevalent about 72.
Pretreatment serum hepatitis C virus RNA levels and hepatitis C virus genotype are the main and independent prognostic factors of sustained response to interferon alfa therapy in chronic hepatitis C.
Simeprevir with pegylated interferon alfa 2a plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-1): A phase 3, randomised, double-blind, placebo-controlled trial.
Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial.
As proper identification of Hepatitis C virus genotype before therapy would lead to effective treatment for optimal duration so this study was initiated to find out the distribution of various Hepatitis C virus genotypes present across Hyderabad where genotype determination prior to therapy is not a common practice.
Variable epidemic histories of hepatitis C virus genotype 2 infection in West Africa and Cameroon.