Iacono et al., "Antiviral therapy decreases hepatic venous pressure gradient
in patients with chronic hepatitis C and advanced fibrosis," The American Journal of Gastroenterology, vol.
Hepatic venous pressure gradient
predicts clinical decompensation in patients with compensated cirrhosis.
Hence, non invasive tests are being tried and Doppler ultrasound is foremost among them as an alternative to endoscopy to predict the varices and also to assess hepatic venous pressure gradient
. Baik and colleagues found a positive correlation between waveform and hepatic vein pressure gradient (HVPG) in their study.10 A normal person showed triphasic waveform of hepatic vein (HV) and in a cirrhotic patient monophasic or biphasic waveform of HV was seen.11,12
Esophageal varices may begin to bleed if the portal pressure, as measured by the hepatic venous pressure gradient
, is greater than 12 mm Hg.