hepatic vein obstruction

Budd Chiari syndrome

A condition defined by obstruction of the hepatic veins and its clinical manifestations, regardless of the cause (except congestive heart failure), where the obstruction is either within the liver on in the inferior vena cava between the liver and the right atrium.
Thrombosis in the hepatic veins (majority of cases) due to coagulation secondary to polycythaemia vera, pregnancy, postpartum, oral contraceptive use, intravascular lesions including malignancy, myeloproliferative disorders, paroxysmal nocturnal haemoglobinuria (PNH), infection (e.g., schistosomiasis), intravascular webs.
Clinical findings
Abdominal pain, ascites, jaundice, hepatomegaly, and eventually cirrhosis, liver failure and hepatic encephalopathy.

Abnormal LFTs, increased liver enzymes.

Liver failure, GI bleeding, starvation.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

hepatic vein obstruction

Budd-Chiari syndrome Hepatology A condition characterized by clotting of blood in the hepatic vein linked to the use of OCs
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Rambaud, "Association of hepatic vein obstruction and coeliac disease in North African subjects," Journal of Hepatology, vol.
The diagnosis was made according to the following criteria (12): i) increased serum bilirubin level ([greater than or equal to] 34.2 [micro]mol/L) without other explainable causes, and ii) hepatomegaly with pain and ascites and an unexplainable weight gain of [greater than or equal to] 2%, or iii) small hepatic vein obstruction, hepatic venous lumen eccentric stenosis and induration, or iv) sinusoidal fibrosis and hepatocellular necrosis in zone three found by percutaneous liver biopsy.
Becker CD, Cooperberg described that hepatic vein obstruction is the presence of echogenic intra luminal material (thrombus or tumor) accompanied by absence of hepatic vein flow.
Pregnancy related Budd-Chiari syndrome is usually an acute disorder with Inferior vena cava and Hepatic vein obstruction with dilatation of the collateral vessels and bleeding (6) along with marked elevation of Alanine transaminase and Aspartate transaminase.