heparan sulfate


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Related to heparan sulfate: keratan sulfate, dermatan sulfate

heparan sulfate

 [hep´ah-ran]
a sulfated mucopolysaccharide structurally related to heparin, which occurs normally in the liver, aorta, and lung; it is an accumulation product in several mucopolysaccharidoses.

hep·a·ran sul·fate

(hep'ă-ran sŭl'fāt),
A heteropolysaccharide that has the same repeating disaccharide as heparin but with fewer sulfates and more acetyl groups; accumulates in people with certain types of mucopolysaccharidosis.
Synonym(s): heparitin sulfate

heparan sulfate

/hep·a·ran sul·fate/ (hep´ah-ran) a glycosaminoglycan occurring in the cell membrane of most cells, consisting of a repeating disaccharide unit of glucosamine and uronic acid residues, which may be acetylated and sulfated; it accumulates in several mucopolysaccharidoses.

heparan sulfate

(hĕp′ə-răn)
n.
A glycosaminoglycan found on cell surfaces and basement membranes in mammals that regulates a wide variety of biological processes, including angiogenesis and blood coagulation. Also called heparitin sulfate.

heparan sulfate

a sulfated mucopolysaccharide structurally related to heparin, which occurs normally in the liver, aorta and lung; it is an accumulation product in several mucopolysaccharidoses.
References in periodicals archive ?
4] Proteomic markers a1-Antitrypsin IgA-Uromodulin Galactose-deficient IgA1 Heparan sulfate
Heparan sulfate and syndecan-1 are essential in maintaining murine and human intestinal epithelial barrier function.
Sperm express molecules known to interact with HIV's envelope, such as heparan sulfate and mannose receptors.
Circulating heparan sulfate anticoagulant in a patient with a fatal bleeding disorder.
Children with Sanfilippo syndrome are missing an essential enzyme that breaks down complex body sugar called heparan sulfate.
Caitlin does not have the essential enzyme that breaks down strings of heparan sulfate, a complex body sugar.
HSV primarily uses heparan sulfate for initial attachment, but other glycosaminoglycans, such as dextran or dermatam sulfate, can substitute in its absence (Deepak and Spear, 2001).
It is a novel anti-cancer compound with a first-in-class mechanism as a heparan sulfate mimetic.
Studies support the opinion that increased urinary albumin excretion reflects renal and generalized transvascular albumin leakage that is possibly due to low vessel wall content of heparan sulfate (7).
Syndecan-2 is but one member of the syndecan family of heparan sulfate proteoglycans.
Mutations in the E2 glycoprotein of Venezuelan equine encephalitis virus confer heparan sulfate interaction, low morbidity, and rapid clearance from blood of mice.