heparan N-sulfatase

hep·a·ran N-sul·fa·tase

(hep'ă-ran sŭl'fă-tās),

An enzyme that participates in the stepwise degradation of heparan sulfate; heparan N-sulfatase hydrolyzes the sulfate moiety attached to the amino group of the glucosamine residue of heparan sulfate; a deficiency of this enzyme is associated with mucopolysaccharidose IIIA (Sanfilippo syndrome A).