hemoglobin SC disease
hemoglobin SC disease
Hematology A sickling disorder resulting from inheritance of a HbS gene from one parent and a HbC gene from the other; RBCs contain ± equal amounts of each Hb; HbA is absent; HbF may be ↑ Clinical Similar to, but less severe than, sickle cell anemia; by preadolescence, episodic skeletal or abdominal pain, moderate splenomegaly; unique to SC disease is an ↑ risk of retinal disease–proliferative retinopathy, retinal vascular disease, aseptic necrosis of femoral head, acute chest syndrome after fat embolism due to bone infarction. See Sickle cell anemia.McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
hemoglobin SC disease
A disease of those who have inherited two abnormal forms of hemoglobin, S and C. The affected may have vaso-occlusive crises similar to those seen in sickle cell anemia, with bony and visceral infarcts.
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