hemoglobin Chesapeake

he·mo·glo·bin Ches·a·peake (HbChesapeake),

[MIM*141800.0018]
an abnormal hemoglobin with a single α-chain substitution, molecular formula α292Arg→Leuβ2A; heterozygotes have polycythemia, apparently to compensate for the increased oxygen affinity of this Hb, resulting in decreased liberation of oxygen in the tissues.
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