hemoglobin C disease
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Related to hemoglobin C disease: hemoglobin SC disease
he·mo·glo·bin C dis·ease
the homozygous state of hemoglobin C.
hemoglobin C diseaseHematology An AR hemoglobinopathy most commonly affecting blacks, characterized by intermittent abdominal pain, arthralgias, headaches, splenomegaly, cholecystitis, gallstones Lab Mild–33% Hct anemia, 2–6% reticulocyte count; 90% of RBCs are targetoid, often with HbC crystals; ↑ iron turnover, ↓ RBC survival. Cf Sickle cell anemia.
Hemoglobin C disease
A disease of abnormal hemoglobin, occurring in 2-3% of African-Americans. Only those who have two genes for the disease develop anemia, which varies in severity. Symptoms include episodes of abdominal and joint pain, an enlarged spleen and mild jaundice.
Mentioned in: Hemoglobin Electrophoresis