hemoglobin Bart

he·mo·glo·bin Bart

[MIM*142309]
a Hb homotetramer (all four polypeptides identical) of formula γ4, found in the early embryo and in α-thalassemia 2; not effective in oxygen transport; does not display a Bohr effect.

hemo·glo·bin Bart

(hē'mō-glō'bin bahrt)
An Hb homotetramer (all four polypeptides identical) of formula γ4, found in the early embryo and in α-thalassemia 2; not effective in oxygen transport; does not display a Bohr effect.
Synonym(s): haemoglobin Bart.
References in periodicals archive ?
It is present in two clinically significant forms: hemoglobin Bart hydrops fetalis (Hb Bart) syndrome and hemoglobin H (HbH) disease.
Since [alpha]-globin chains are absent, hemoglobin F cannot be synthesized and hemoglobin Bart's becomes the dominant hemoglobin.
In some cases, a small amount of hemoglobin Bart's may be present.