hemoglobin A2


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he·mo·glo·bin A2

[MIM*141850]
the normal Hb (Hb A2) of the formula α2Aδ2 or α2δ2, which makes up approximately 2.5% of the total adult hemoglobin concentration. At least 18 mutant variants of the δ chain have been reported.
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Other data included hemoglobin (Hb), MCV, MCH, mean corpuscular hemoglobin concentration (MCHC), hemoglobin F (HbF) and hemoglobin A2 (HbA2).
Insulin-like growth factor-1 levels in children with beta-thalassemia minor/Beta-talasemi minorlu cocuklarda insulin-benzeri buyume faktoru-1 seviyeleri
Hemoglobin A2' (Hb A2[delta]') in the Mauritanian population: first results of a preliminary survey.
HPLC retention time as a diagnostic tool for hemoglobin variants and hemoglobinopathies: a study of 60 000 samples in a clinical diagnostic laboratory
An evaluation of the methods for quantitation of hemoglobin A2. Results from a survey of 10,663 cases.
Prenatal and postnatal diagnoses of thalassemias and hemoglobinopathies by HPLC
The detection and diagnosis of hemoglobin A2' by high-performance liquid chromatography.AmJ Clin Pathol 2005; 123:657-61.
A Primed Hemoglobinopathy Screen
Subsequent hemoglobin electrophoresis revealed 17.5% of hemoglobin A (normal 94%-98%), 7.2% of hemoglobin A2 (normal 0.7%-3.1%), 73.8% of hemoglobin S (normal 0%), and 1.5% of hemoglobin F (normal 0-2%), which was suggestive of sickle cell beta-plus thalassemia.
Sickle Cell Beta-Plus Thalassemia with Subcapsular Hematoma of the Spleen
Values Baseline Final Parameters Mean 95% CI Mean 95% CI Mean variation Blood count before and after one RCE (N Red cells count 3,1 2,9-3,3 3,3 3,1-3,4 +0,2 ([10.sup.12]/L) Hemoglobin rate 8,9 8,6-9,1 10,3 8,5-12,2 +1,4 (g/dL) Hematocrit (%) 26,2 24,7-27,8 30,6 23,3-37,6 +4,4 White cells count 11,5 10,7-12,2 11,6 10,4-12,7 +0,1 ([10.sup.9]/L) Platelets count 443 414-473 433 401-475 -10 ([10.sup.9]/L) Fractions of hemoglobin before and after 2 RCE performed the day of admission (N = 12) Hemoglobin S (%) 84,8 80,5-89 24,8 20,6-32 -60 Hemoglobin A (%) 0 -- 64 58-70 +64 Hemoglobin F (%) 10,2 8,0-12,5 6 3,0-7,5 -4,2 Hemoglobin A2 (%) 3,3 2,9-3,7 2,3 1,9-3,0 -1
Efficacy and Safety of Manual Partial Red Cell Exchange in the Management of Severe Complications of Sickle Cell Disease in a Developing Country
Hemoglobin A2 of more than 3.5% was considered diagnostic for beta-thalassemia trait.
INCIDENCE OF b-THALASSEMIA CARRIERS IN MUZAFFARABAD, AZAD JAMMU AND KASHMIR
Phenotypic expression of hemoglobin A2 in beta-thalassemia trait with iron deficiency.
An evaluation of thyroid autoimmunity in patients with beta thalassemia minor: A case-control study
The range of hemoglobin A2 in hemoglobin E heterozygotes as determined by capillary electrophoresis.
Detection of hemoglobinopathies and thalassemias using automated separation systems
del Pilar Aguinaga, "Chromatographic measurements of hemoglobin A2 in blood samples that contain sickle hemoglobin," Annals of Clinical & Laboratory Science, vol.
Detection of abnormal hemoglobin variants by HPLC method: common problems with suggested solutions
A small percentage of hemoglobin A2 and hemoglobin F is also present in the population, Hemoglobin F is predominately in fetuses and newborns.
Thalassemias
Hemoglobin A2 was analyzed by micro column technique from Bio Systems kits and hemoglobin F was assayed by alkaline denaturation technical.
Evaluation of hemoglobinopathy screening results of a six year period in Turkey

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