Phenotypic expression of hemoglobin A2
in beta-thalassemia trait with iron deficiency.
6 Normal Person Sickle-cell syndrome P1 ([female]) HbAS P2 ([male]) HbAS/[alpha] thal P3 ([male]) HbAS/[beta] thal P4 ([male]) HbAS/[alpha] thal P5 ([female]) HbAS P6 ([female]) HbAS P7 ([male]) HbAS/[beta] thal References: Solubility: Reference value: negative, positive sickle cells: presence of drepanocytes; Electrophoresis: Values: Hemoglobin A1 (96-98%); Hemoglobin A2
Significance of borderline hemoglobin A2
values in an Italian population with a high prevalence of [beta]-thalassemia," Haematologica, vol.
The range of hemoglobin A2
in hemoglobin E heterozygotes as determined by capillary electrophoresis.
A small percentage of hemoglobin A2
and hemoglobin F is also present in the population, Hemoglobin F is predominately in fetuses and newborns.
was analyzed by micro column technique from Bio Systems kits and hemoglobin F was assayed by alkaline denaturation technical.
Interference of hemoglobin D in hemoglobin A2
measurement by cation-exchange HPLC.
duzeyi ise olgularin %95'inde artmistir (>%3,4).
Quantification of hemoglobin A2
by tandem mass spectrometry.
Results: A total of one hundred and thirty-five individuals with hypochromic microcytic anemia having normal hemoglobin F and hemoglobin A2
In both alpha and beta thalassemia, significant mi-crocytosis (decreased MCV and/or MCH) is usually present, and in beta thalassemia, elevations in hemoglobin A2
are also usually detected.