Subsequent hemoglobin electrophoresis revealed 17.5% of hemoglobin A (normal 94%-98%), 7.2% of
hemoglobin A2 (normal 0.7%-3.1%), 73.8% of hemoglobin S (normal 0%), and 1.5% of hemoglobin F (normal 0-2%), which was suggestive of sickle cell beta-plus thalassemia.
Values Baseline Final Parameters Mean 95% CI Mean 95% CI Mean variation Blood count before and after one RCE (N Red cells count 3,1 2,9-3,3 3,3 3,1-3,4 +0,2 ([10.sup.12]/L) Hemoglobin rate 8,9 8,6-9,1 10,3 8,5-12,2 +1,4 (g/dL) Hematocrit (%) 26,2 24,7-27,8 30,6 23,3-37,6 +4,4 White cells count 11,5 10,7-12,2 11,6 10,4-12,7 +0,1 ([10.sup.9]/L) Platelets count 443 414-473 433 401-475 -10 ([10.sup.9]/L) Fractions of hemoglobin before and after 2 RCE performed the day of admission (N = 12) Hemoglobin S (%) 84,8 80,5-89 24,8 20,6-32 -60 Hemoglobin A (%) 0 -- 64 58-70 +64 Hemoglobin F (%) 10,2 8,0-12,5 6 3,0-7,5 -4,2
Hemoglobin A2 (%) 3,3 2,9-3,7 2,3 1,9-3,0 -1