hemizygous


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hem·i·zy·gous

(hem'ē-zī'gŭs),
Pertaining to a gene of which only one copy is present in an organism having diploid cells. In human beings, refers to genes on the X chromosome in males, which are expressed whether dominant or recessive.
Synonym(s): hemizygotic

hem·i·zy·gous

(hem'ē-zī'gŭs)
Having unpaired genes in an otherwise diploid cell; males are normally hemizygous for genes on both sex chromosomes.
Synonym(s): hemizygotic.

hemizygous

(of a DIPLOID (2) organism) possessing only one allele of a gene, rather than the normal two. For example, male mammals have only one copy of each gene on the single X-chromosome. see SEX LINKAGE.
References in periodicals archive ?
1] population where the segregation ratio for two hemizygous plants of transgenic parent Cot63 16b#1 and one hemizygous plant of transgenic parent Cot138 E3#17 failed to produce sufficient tolerant genotypes to fit the expected 1:1 or 3:1 [R.
021a Percent of total soluble protein Hemizygous Background([double dagger]) N Mean [+ or -] SE cryIA (b) gene C312/CAMD-E 21 0.
To facilitate heteroduplex formation, samples from hemizygous males were mixed with samples of male wild-type DNA (1:1 w/w) before PCR amplification.
RFLP markers identified four lines apparently hemizygous for a P-genome marker, divided the 23 lines into 17 groups, and verified parentage of the 40-chromosome [F.
HIF [sup]flox/- mice were generated from HIF-1a loxP-flanked allele mouse stocks backcrossed into a C57Bl6/J background, and then crossed into MCK-Cre [sup]+ hemizygous mice [Figure 1].
Since males were hemizygous for chromosome X, we only analyzed maternal inheritance of the X-linked mutations.
Hemizygous TRAMP males manifest progressive prostate tumors that begin as early prostatic intraepithelial neoplasia (PIN) and can progress to differentiated adenocarcinoma.
Further investigation revealed that this heterogeneity was caused by different methods of measuring p16 (fluorescence in situ hybridization) and studying the influence of hemizygous or homozygous deletion of p16 on patient prognosis.
Ser113Phe can be associated with SV CAH if found in a homo- or hemizygous state.
Heterozygous APP/PS1 double-transgenic mice (APPswe-PS1dE9) were crossed with nontransgenic female mice (the Model Animal Research Center of Nanjing University, Jiangsu, China) to produce hemizygous transgenic mice and nontransgenic littermates.
fl/fl] mice were bred to hemizygous transgenic male Cre mice under control of an adiponectin/promoter/ enhancer [B6;FVB-Tg(Adipoq-cre)1Evdr/J; The Jackson Laboratory].