hemizygous


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hem·i·zy·gous

(hem'ē-zī'gŭs),
Pertaining to a gene of which only one copy is present in an organism having diploid cells. In human beings, refers to genes on the X chromosome in males, which are expressed whether dominant or recessive.
Synonym(s): hemizygotic
Farlex Partner Medical Dictionary © Farlex 2012

hem·i·zy·gous

(hem'ē-zī'gŭs)
Having unpaired genes in an otherwise diploid cell; males are normally hemizygous for genes on both sex chromosomes.
Synonym(s): hemizygotic.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

hemizygous

(of a DIPLOID (2) organism) possessing only one allele of a gene, rather than the normal two. For example, male mammals have only one copy of each gene on the single X-chromosome. see SEX LINKAGE.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Sanger sequencing confirmed that while the proband is hemizygous for this mutation, his mother is heterozygous for this mutation.
By comparing the behavioral results obtained in this study with literature data (Table 1), we found that heterozygous Cdkl5 KO females develop behavioral abnormalities that are comparable, albeit milder, to defects identified in homozygous Cdkl5 KO (Cdkl5 -/-) female and hemizygous Cdkl5 KO (Cdkl5 -/Y) male mice.
Two hemizygous deletions (2, 0) affect chromosome 11p15.5-p11.12 and 11q11- q13.1.
However, it has been difficult to define the precise population frequencies of the various RH haplotypes because of the inability to differentiate between homo- or hemizygous individuals.
HIF [sup]flox/- mice were generated from HIF-1a loxP-flanked allele mouse stocks backcrossed into a C57Bl6/J background, and then crossed into MCK-Cre [sup]+ hemizygous mice [Figure 1].
Williams-Beuren syndrome (WBS) is a rare multisystem disorder caused by a hemizygous deletion of the elastin gene on chromosome 7q11.23 [1].
It is an X-linked disorder, in which hemizygous males are almost always symptomatic and about 20% of female carriers, may present some neurocognitive deficit depending on lyonization patterns [9,10].
Miners, "Anderson-Fabry disease: clinical manifestations and impact of disease in a cohort of 98 hemizygous males," Journal of Medical Genetics, vol.
Moreover, the esophagus extrinsic veins drain into the locally corresponding large vessels (the jugular veins or the azygos and hemizygous veins superiorly and to the left gastric and splenic veins inferiorly).
Female [AhR.sup.fl/fl] mice were bred to hemizygous transgenic male Cre mice under control of an adiponectin/promoter/ enhancer [B6;FVB-Tg(Adipoq-cre)1Evdr/J; The Jackson Laboratory].