1] population where the segregation ratio for two hemizygous
plants of transgenic parent Cot63 16b#1 and one hemizygous
plant of transgenic parent Cot138 E3#17 failed to produce sufficient tolerant genotypes to fit the expected 1:1 or 3:1 [R.
021a Percent of total soluble protein Hemizygous
Background([double dagger]) N Mean [+ or -] SE cryIA (b) gene C312/CAMD-E 21 0.
To facilitate heteroduplex formation, samples from hemizygous
males were mixed with samples of male wild-type DNA (1:1 w/w) before PCR amplification.
RFLP markers identified four lines apparently hemizygous
for a P-genome marker, divided the 23 lines into 17 groups, and verified parentage of the 40-chromosome [F.
HIF [sup]flox/- mice were generated from HIF-1a loxP-flanked allele mouse stocks backcrossed into a C57Bl6/J background, and then crossed into MCK-Cre [sup]+ hemizygous
mice [Figure 1].
Since males were hemizygous
for chromosome X, we only analyzed maternal inheritance of the X-linked mutations.
TRAMP males manifest progressive prostate tumors that begin as early prostatic intraepithelial neoplasia (PIN) and can progress to differentiated adenocarcinoma.
Further investigation revealed that this heterogeneity was caused by different methods of measuring p16 (fluorescence in situ hybridization) and studying the influence of hemizygous
or homozygous deletion of p16 on patient prognosis.
Ser113Phe can be associated with SV CAH if found in a homo- or hemizygous
Heterozygous APP/PS1 double-transgenic mice (APPswe-PS1dE9) were crossed with nontransgenic female mice (the Model Animal Research Center of Nanjing University, Jiangsu, China) to produce hemizygous
transgenic mice and nontransgenic littermates.
fl/fl] mice were bred to hemizygous
transgenic male Cre mice under control of an adiponectin/promoter/ enhancer [B6;FVB-Tg(Adipoq-cre)1Evdr/J; The Jackson Laboratory].
Moreover, for RN line all sample were female, showing hemizygous
for this locus.