hemizygote


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Related to hemizygote: heterozygous, homozygote, homozygous

hemizygote

 [hem″e-zi´gōt]
an individual exhibiting hemizygosity, such as males with the X chromosome.

hem·i·zy·gote

(hem'ē-zī'gōt),
An individual hemizygous with respect to one or more specified loci; for example, a normal male is a hemizygote with respect to the gene for all X-linked or Y-linked genes in his genome.
[hemi- + G. zygōtos, yoked]

hemizygote

[-zī′gōt]
Etymology: Gk, hemi + zygon, yoke
an individual, organism, or cell that has only one allele for a specific characteristic. The trait specified by the allele is expressed regardless of whether the allele is dominant or recessive. Such alleles include those on the single X chromosome in males, which have no corresponding alleles on the Y chromosome. hemizygosity, n., hemizygotic, hemizygous, adj.

hem·i·zy·gote

(hem'ē-zī'gōt)
An individual hemizygous with respect to one or more specified loci; e.g., a normal male is a hemizygote with respect to the gene for all X-linked or Y-linked genes in his genome.
[hemi- + G. zygōtos, yoked]

hemizygote

an animal exhibiting hemizygosity.
References in periodicals archive ?
Although the concentration of lysoGb3 in plasma samples of male Fabry hemizygotes was 100 times higher than in those of healthy individuals, the wide linear dynamic range and the great sensitivity allowed accurate quantification in both groups (Fig.
We then examined this permutation of sphingolipids in the Fabry hemizygotes according to their genotypes (Fig.
As shown in Table 1, the concentration of the total PC was higher in the heterozygotes than in either the control group or the hemizygotes, thus indicating greater urinary sediment in the former.
The measurement of CTH on its own was not sufficient to identify all Fabry patients, although the SM C22:0 species did provide complete differentiation between the hemizygotes and the control group (Table 1).
A more extensive study of Fabry hemizygotes covering many more phenotypes/genotypes is needed if this lipid-profiling approach is to be evaluated for predicting disease severity in Fabry patients.
The use of lipid profiles to diagnose Fabry hemizygotes and identify heterozygotes has positive implications, not only for genetic counseling purposes, but so that consideration can be given for prophylactic treatment for these individuals.
Fabry's disease: enzymatic diagnosis of hemizygotes and heterozygotes.
alpha]-GALACTOSIDASE AND SAPOSIN C IN BLOOD SPOTS FROM ADULT AND NEWBORN CONTROLS, FABRY HEMIZYGOTES, AND HETEROZYGOTES
All Fabry hemizygotes had [alpha]-galactosidase activities below the detection limit of the assay [0.
alpha]-GALACTOSIDASE AND SAPOSIN C IN PLASMA FROM CONTROLS, FABRY HEMIZYGOTES, AND HETEROZYGOTES
Plasma samples from normal controls (n = 49) Fabry hemizygotes (n = 26), and heterozygotes (n = 3) were assayed for [alpha]-galactosidase protein concentration and activity and for saposin C (Fig.
There was no overlap between the control range and the Fabry hemizygotes for [alpha]-galactosidase protein (Fig.