The clinical features of Beckwith-Wiedemann syndrome (BWS) include hemihypertrophy
The presentation may be in the form of multiple echo lucent areas suggestive of cutaneous vascular malformations  and/or hemihypertrophy
of a lower extremity .
On extraoral examination, a hemihypertrophy
was observed on the right side of the face extending from hairline till lower border of mandible along the division of the trigeminal nerve with PWS which was present since birth [Figure 1].
BWS is associated with increased growth within the first few years of life, manifesting as hemihypertrophy
, hemihypaesthesia, hemiareflexia and scoliosis," Brain, vol.
Parkes-Weber, "Angioma formation in connection with hypertrophy of limbs and hemihypertrophy
," British Journal of Dermatology, vol.
Infrapelvic causes of obliquity that are important to consider include fractures, LLD due to previous polio infection, hemihypertrophy
, and so forth.
Circumference difference of extremities may result from congenital or acquired diseases causing hemihypertrophy
phlebitis or major venous insufficiency.
Brain abnormalities of Klippel-Trenaunay-Weber syndrome include hemorrhage, infarction, hydrocephalus, cerebral or cerebellar hemihypertrophy
, cerebral calcifications, vascular malformation, cavernoma, arteriovenous malformations, aneurysm, choroid plexus abnormalities, cortical dysplasia, leptomeningeal enhancement [4, 5].
Abnormal asymmetric growth and hemihypertrophy
are its typical clinical manifestations, though overgrowth of the long bones, macrodactyly, asymmetric macrocephaly, plantar or palmar hyperplasia, vertebral abnormalities, lipoma, hemangioma, connective tissue nevi, lymphangiomas, and vascular malformations can also be observed in this syndrome [7, 23-25].
The Proteus syndrome: partial gingantism of the hands and/or feet, nevi, hemihypertrophy
, subcutaneous tumours, macrocephaly or other skull anomalies and possible growth and visceral affections.
Proteus syndrome presenting with hemihypertrophy
consisting of lipomatous tumor is similar to macrodystrophia lipomatosa.