The differential diagnosis of our case of progressive hemifacial atrophy includes other forms of juvenile localized scleroderma, Barraquer-Simons syndrome, congenital
hemiatrophy, and primary hemifacial hypertrophy.
Gutierrez LJ, Oliva NP Progressive facial
hemiatrophy with associated osseous lesions.
Recent fluorodeoxyglucose-positron emission tomography (FDG-PET) studies proved hypometabolism of the affected hemisphere [8, 9], whereas other studies have suggested that a reduced blood flow through carotid artery due to co-arctation could be the cause of cerebral
hemiatrophy [9, 10].
The radiological features of DDMS are distinctive, and may include cerebral
hemiatrophy with several parenchymal changes and ipsilateral compensatory hypertrophy of the skull bone and sinuses.
Progressive facial
hemiatrophy began when the woman was only 11 years old.
Parry-Romberg syndrome (progressive facial
hemiatrophy)
The diagnosis of DDMS was based on facial asymmetry, hemiplegia, mental retardation, and cerebral
hemiatrophy. The diagnosis of MS was established on the characteristics of tall stature, intermaxillary narrowness, myopia, retinitis pigmentosa, blue sclera, scoliosis, pectus excavatum, arachnodactyly and diminished ratio of Us/Ls.
Differential diagnoses that should be considered in patients with asymptomatic enophthalmos are Parry-Romberg syndrome (facial
hemiatrophy), linear scleroderma, metastasis, osteomyelitis, atrophy of the orbital contents, orbital varix, chronic sinusitis, cysts, and pseudoenophthalmos, among others.
Similarly, the use of pieces of adipose tissue and artificial tissue substitutes such as silicon, collagen and hydroxyapatite for soft tissue augmentation in facial
hemiatrophy, hypomastia, mammoplasty and other deformities again face safety issues.
The possible results of first-trimester maternal infection--the congenital varicella syndrome, characterized by cerebral
hemiatrophy and abnormalities of the extremities and skin--are well known.
The possible results of first-trimester maternal infection--the con genital varicella syndrome, characterized by cerebral
hemiatrophy and abnormalities of the extremities and skin--are well known.