(2012) Heme oxygenase
, a novel target for the treatment of hypertension and obesity?
Physiologically, CO is generated by two heme oxygenases
, hemeoxygenase-1 (HO-1) and hemeoxygenase-2 (HO-2), which catalyze the catabolism of heme groups .
Teng et al., "Cobalt-protoporphyrin enhances heme oxygenase
1 expression and attenuates liver ischemia/reperfusion injury by inhibiting apoptosis," Molecular Medicine Reports, 2018.
, which was also found in the transcripts of the host and symbiont, is important for producing biliverdin.
Choi, "Heme oxygenase
: colors of defense against cellular stress," American Journal of Physiology, vol.
Caption: FIGURE 6: Proposed mechanism of heme oxygenase
inducer application to overcome accumulation of toxic metabolites [102,104,105] induced by NSAIDs.
The nuclear translocation of Nrf2 was associated with increased expression of Nrf2 target genes heme oxygenase
1 (HO-1, p < 0.001), glutamate-cysteine ligase catalytic subunit (GCLC, p = 0.04) and glutamate-cysteine ligase regulatory subunit (GCLM, p <0.001) (Figure 4(c)).
Cobalt induction of hepatic heme oxygenase
; with evidence that cytochrome P-450 is not essential for this enzyme activity.
Products of heme oxygenase
and their potential therapeutic applications.
The heme oxygenase
system: a regulator of second messenger gases.
Chen, "Adenovirus-mediated heme oxygenase
transfer inhibits graft arteriosclerosis in rat aortic transplants," Transplantation Proceedings, vol.
The study also involved estimating the following parameters in the patient population- digoxin, bile acid, hexokinase, porphyrins, pyruvate, glutamate, ammonia, acetyl CoA, acetyl choline, HMG CoA reductase, cytochrome C, blood ATP, ATP synthase, ERV RNA (endogenous retroviral RNA), H2O2 (hydrogen peroxide), NOX (NADPH oxidase), TNF alpha and heme oxygenase