While the color additive review process is more stringent than the GRAS one, he said, rejection of heme as
a color additive after it's already gone through GRAS is "very unlikely."
a magnificent molecule with multiple missions: heme determines its own fate and governs cellular homeostasis.
For this purpose, we tested the AhbAB activity in an in vitro enzyme activity assay in the absence and presence of different amounts of added heme as described in the Materials and Methods section.
The compound at 37.5 min retention time was heme as revealed by comparison with the chromatographic behavior of a hemin standard (see also Figure 3(c)).
Our group characterized free heme as
a proinflammatory agent, able to activate polymorphonuclear neutrophils (PMN) and delay the spontaneous apoptosis of these cells by a mechanism that relies on NADPHox-generated ROS [8, 26, 27].
Pathogenic bacteria utilize heme as
a source to obtain the iron necessary for their survival and ability to establish an infection.