hematoporphyrin derivative


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hematoporphyrin derivative

Oncology An agent used in photodynamic therapy that is absorbed by tumor cells which is activated when exposed to light, killing tumor cells. See Photodynamic therapy.
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Hydrogen peroxide, superoxide, and hydroxyl radicals are involved in the phototoxic action of hematoporphyrin derivative against tumor cells.
Hydrogen peroxide and hydroxyl free radical production by hematoporphyrin derivative, ascorbate and light.
Photodynamic generation of hydroxyl radicals by hematoporphyrin derivative and light.
Photooxidation of hematoporphyrin derivative bovine serum albumin complex.
Superoxide, hydrogen peroxide and singlet oxygen in hematoporphyrin derivative cysteine, -NADH and -light systems.
Photooxidation of cell membranes in the presence of hematoporphyrin derivative: reactivity of phospholipid and cholesterol hydroperoxides with glutathione peroxidase.