hematoporphyrin


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Related to hematoporphyrin: hematoporphyrin derivative

hematoporphyrin

 [he″mah-to-por´fĭ-rin]
a hematogenous pigment that is an iron-free derivative of heme, a product of the decomposition of hemoglobin.

he·ma·to·por·phy·rin

(hē'mă-tō-pōr'fi-rin, hem'ă-),
A dark red, almost purple, porphyrin resulting from the decomposition of hemoglobin; chemical composition is that of heme with the iron removed and the two vinyl (-CH=CH2) groups hydrated to hydroxyethyl (-CH(OH)-CH3).
Synonym(s): hemoporphyrin

he·ma·to·por·phy·rin

(hē'mă-tō-pōr'fir-in)
A porphyrin resulting from the decomposition of hemoglobin; chemical composition is that of heme with the iron removed and the two vinyl groups hydrated to hydroxyethyl.
Synonym(s): hemoporphyrin, haematoporphyrin.
References in periodicals archive ?
The oxygen-binding properties of hemoglobin were evaluated by examining changes in the conformation of hemoglobin hematoporphyrin in native erythrocytes by means of Raman spectroscopy using an inVia Raman-scattering spectrometer (Renishaw, United Kingdom) with a short focal distance and high transmission monochromator with a focal distance no longer than 250 mm.
used GNR/Si[O.sub.2]-HP (hematoporphyrin) complex to implement synergistic PDT + PTT treatments of large (about 3 [cm.sup.3]) solid tumors in vivo for the first time.
'The Sensitizing Action of Hematoporphyrin,' Biochemische Zeitschrift, 30:276-316, 1911.
Hematoporphyrin photodynamic therapy: Is there truly a future in head and neck oncology?
In addition, photodynamic therapy with hematoporphyrin derivative (HPD) may be useful in treating these melanomas.
This dye, known initially as hematoporphyrin derivative (Hpd) and in purified form as Photofrin II, has been used to treat about 5,000 patients worldwide for many kinds of solid tumors, including those of the skin, lung, bladder, eye, head, neck and esophagus.
Joffe, "Hematoporphyrin derivative uptake and photodynamic therapy in pancreatic carcinoma," Journal of Surgical Oncology, vol.
(7) First genetation include photofrin (most extensively used) and hematoporphyrin derivatives (HPD).
Effects of light exposure on the uptake and destruction of hematoporphyrin derivative in Ehrlich carcinoma cell suspension.
In addition, chemical treatment could perhaps yield some hematoporphyrin, with a loss of fluorescence, whereas enzymatic digestion could produce porphyrin-peptide fragments (X porphyrins) with a loss of stoichiometric relationships.