hematopoietic growth factor


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he·ma·to·poi·et·ic growth fac·tor

(HGF) (hē'mă-tō-poy-et'ik grōth fak'tŏr)
Any of several glycoproteins that regulate the survival, self-renewal, proliferation, and differentiation of hematopoietic progenitor cells. There are two nomenclature groups: interleukins (IL) and colony-stimulating factors (CSF).
Synonym(s): haematopoietic growth factor.

hematopoietic growth factor

Any of a group of at least seventeen substances involved in the production of blood cells, including several interleukins and erythropoietin.
See also: factor
References in periodicals archive ?
Inhibitors of cytokine actions have utility in the use of the anti-IL-2 receptor for reducing graft rejection in transplant patients, in the use of hematopoietic growth factors to reverse acute events that arise from chemotherapy or radiation therapy of certain cancer types or in the treatment of certain immunodeficiency disorders.
(32,70-74) On the other hand, p38 MAPKs may also play critical roles in the production of hematopoietic growth factors. For example, studies have shown that disruption of p38[alpha] leads to decreasing erythropoietin gene expression in mice.
* Hematologic toxicities may occur with capecitabine and can be managed with dose modification or hematopoietic growth factors.
Nausea, vomiting, and neutropenia used to be the most serious adverse effects of chemotherapy and radiation therapy, but new antiemetic agents and hematopoietic growth factors have reduced the magnitude of these problems, Dr.

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