hematologic effect

hematologic effect

the response of blood cells to radiation exposure. All types of blood cells are destroyed by radiation, and the degree of cell depletion increases with increasing dose. Lymphocytes are affected first and are reduced in number within minutes or hours after exposure. Erythrocytes are less sensitive than other types of blood cells and may not show radiation effects for several weeks.
References in periodicals archive ?
Decreased platelet count is the most common and best recognized hematologic effect of valproic acid; the incidence varies from 5% to 40%.
Side effects of VPA include GI distress (eg, anorexia, nausea, dyspepsia, vomiting, diarrhea), hematologic effects (reversible leukopenia, thrombocytopenia), hair loss, weight gain, tremor, hepatic effects (benign LFT elevations, hepatotoxicity), osteoporosis, and sedation.
CONTEXT: Although there are ample data on the respiratory effects of exposure to fire extinguisher gas, the potential hematologic effects have not been fully documented.
Special Considerations: Gastrointestinal tract symptoms (vomiting, nausea, and diarrhea); hematologic effects (anemia, leukopenia, thrombocytopenia, neutropenia, and febrile neutropenia); and infection were the most common adverse events in a clinical study of 113 pediatric patients.
The hematologic effects of hydroxyurea are the same in children [as in adults], perhaps better," Dr.
Hematologic effects, such as thrombotic thrombocytopenic (Ticlid) purpura, are rare but severe.