hematin


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Related to hematin: haematin, porphyria

hematin

 [he´mah-tin]
1. the hydroxide of heme; it stimulates the synthesis of globin, inhibits the synthesis of porphyrin, and is a component of cytochromes and peroxidases; it is also used as a reagent.
2. hemin (def. 1).

he·ma·tin

(hē'mă-tin, hem'ă-),
Heme in which the iron is Fe(III); the prosthetic group of methemoglobin.

hematin

/he·ma·tin/ (he´mah-tin)
1. the hydroxide of heme; it stimulates the synthesis of globin, inhibits the synthesis of porphyrin, and is a component of cytochromes and peroxidases; it is also used as a reagent.
2. hemin (1).

hematin

(hē′mə-tĭn)
n.
A blue to blackish-brown compound, C34H32N4O4·FeOH, formed in the decomposition of hemoglobin.

he·ma·tin

(hē'mă-tin)
Heme in which the iron is Fe(III) (Fe3+); the prosthetic group of methemoglobin.
Synonym(s): ferriheme, hematosin, oxyheme, oxyhemochromogen, haematin.

Hematin

A drug administered intravenously to halt an acute porphyria attack. It causes heme biosynthesis to decrease, preventing the further accumulation of heme precursors.
Mentioned in: Porphyrias

hematin

a compound formed by the oxidation of heme from the ferrous Fe(II) to the ferric Fe(III) state; it does not combine with oxygen.

hematin methods
basic method of estimating hemoglobin content of blood by converting it to acid hematin and doing a colorimetric estimation. See also hemoglobinometer.
References in periodicals archive ?
B, The fresh encephalon has a pink-beige cortex that turns gray after formalin fixation (heme turned into hematin, see also Figure 3, B.
Data Source: The mean change in menstrual blood loss volume was quantified using the alkaline hematin method.
To make HTM, first a fresh hematin stock solution is prepared by dissolving 50 mg of bovine hematin powder in 100 ml of 0.
In this work, the conducting molecular complex of poly(3,4-ethylenedioxythiophene) (PEDOT)/charged silica template was synthesized by the in situ biomimetic polymerization using hydrogen peroxide and poly(ethylene glycol)-modified hematin (PEG-hematin) as initiator and catalyst, respectively.
Hematin is a complex red organic pigment containing iron for binding oxygen.
2) In this classic study, Hallberg and colleagues collected menstrual pads and tampons from the women and used the alkaline hematin method to estimate blood loss.
Catalase is a major antioxidant enzyme with hematin as the prosthetic group and it is ubiquitously present in all aerobic cells containing a cytochrome system.
Why markers of hemolysis are subsequently present in the peripheral circulation is not known, but the authors, nonetheless, identified increased serum hemoglobin, hematin, lactate dehydrogenase and erythrocyte-derived catalase, and decreased haptoglobin in these patients.
She received infusions of glucose and hematin, which gave her symptomatic relief.
The primary endpoint in Phase 3 studies will be the same as in the Phase 2b study: reduction in uterine blood flow as measured by the alkaline hematin method.