hemangioblastoma


Also found in: Dictionary, Wikipedia.

hemangioblastoma

 [he-man″je-o-blas-to´mah]
a benign blood vessel tumor of the cerebellum, spinal cord, or retina, consisting of proliferated blood vessel cells and angioblasts. Those arising in the cerebellum (cerebellar hemangioblastoma) may be cystic and associated with von hippel-lindau disease. Called also angioblastoma.
cerebellar hemangioblastoma hemangioblastoma of the cerebellum, often cystic; an autosomal dominant form is associated with von Hippel-Lindau disease.

he·man·gi·o·blas·to·ma

(he-man'jē-ō-blas-tō'mă),
A benign neoplasm frequently arising in the cerebellum composed of capillary vessel-forming endothelial cells and stromal cells; a slowly growing tumor that affects, primarily, middle-aged individuals; increased incidence in von Hippel-Lindau disease.

Hemangioblastoma

(1) A tumour of soft tissues, which is of intermediate aggressiveness and thus preferably known as hemangioendothelioma.
(2) A vascularised cerebellar tumour, representing 2% of CNS neoplasms, which occurs in the 3rd–4th decades, either alone or associated with von-Hippel-Lindau syndrome, phaeochromocytoma, syringomyelia or erythrocythemia. 

Management
Excision.
 
Prognosis
Good.

he·man·gi·o·blas·to·ma

(hē-man'jē-ō-blas-tō'mă)
A benign cerebellar neoplasm composed of capillary vessel-forming endothelial cells and stromal cells; a slowly growing tumor that affects, primarily, middle-aged individuals; increased incidence in von Hippel-Lindau disease.
Synonym(s): angioblastoma, Lindau tumor, haemangioblastoma.

Lindau,

Arvid Wilhelm, Swedish pathologist, 1892-1958.
Lindau disease - Synonym(s): von Hippel-Lindau syndrome
Lindau tumor - a benign cerebellar neoplasm. Synonym(s): hemangioblastoma
von Hippel-Lindau syndrome - see under von Hippel
References in periodicals archive ?
2215-7840, 4(1) Preoperative endovascular embolization of a cerebellar hemangioblastoma.
VHL Type 1 is characterized by tumor structures such as central nervous system or retinal hemangioblastoma, but no pheochromocytoma.
Metastatic clear cell renal cell carcinoma (CCRCC) can bear a striking similarity to hemangioblastoma. CCRCC is usually positive for PAX8 and CAIX and negative for S100 and inhibin-A.
For the central nervous system (CNS), it has been reported that screening hemangioblastomas in asymptomatic individuals was not indicated since surgery was considered only in symptomatic subjects.
The main diagnostic considerations are hemangioblastoma (particularly in the absence of homogenous enhancement), metastatic disease, ependymoma, or a choroid plexus tumor.
Indeed, the expression of this protein has been also documented in hemangioblastoma (HBL) [6, 7, 13, 14], a slow growing vascular tumour, which origins from mesoderm derived, embryologically arrested hemangioblasts [4, 13], which also express this protein [15].
Pathological satiety caused by brainstem hemangioblastoma. J Neurosurg Pediatr 2008;2: 397-401.
(2,4,10) The appearance of a cavernous malformation with edema may be unclear and mimic other lesions such as neoplasm, including ependymoma, astrocytoma, hemangioblastoma, metastasis, multiple sclerosis plaque, and arteriovenous malformation.
(1.) Agostinelli C, Roncaroli F, Galassi E, Bernardi B, Acciarri N, Tani G: Leptomeningeal Hemangioblastoma: Case Illustration.