In addition, there were heliotrope rash
and dyspepsia in a patient with pancreatic cancer.
On the following day, we observed newly formed heliotrope rash
on both upper eyelids and keratotic rash along the surface of the fingers of both hands.
The skin manifestations on the neck, face, upper extremities, and dorsum of the hands were photosensitivity consisting of Gottron's papules and a heliotrope rash
, findings consistent with juvenile dermatomyositis.
Three years later, she developed heliotrope rash
and periorbital oedema with no evidence of muscle weakness and was labeled as amyopathic dermatomyositis.
Clinically, amyopathic dermatomyositis (CADM) is a variant phenotype of dermatomyositis defined by characteristic skin manifestations such as a heliotrope rash
and Gottron's papules (1), but little or no evidence of myopathy_ENREF_2.
Clinical manifestations include muscle weakness and skin lesions such as heliotrope rash
and Gottron's papules.
The typical dermatological presentation consists of a erythematous and oedematous periorbital rash--the Heliotrope rash
(3) Characteristic skin manifestations include heliotrope rash
, periungual telangiectasia, edema, and facial erythema, with the hallmark being Gottron's papules--scaling, erythematous eruptions over the knuckles and other extensor surfaces.
Dermatomyositis presents with proximal muscle weakness and skin changes with classic findings of a heliotrope rash
and gottron papules.
Multicenter This study study * Anti-Mi-2 (+) pts., number (%) 9/376 (2.4) 7/124 (5.6) Age at onset, median (range), y 45 (16-66) 62 (40-73) Sex, M/F, number 6/3 1/6 Diagnosis, % Classical DM 100 100 Clinically amyopathic DM 0 0 Clinical features, % Muscle weakness 100 100 Arthritis 11 14 ILD 11 0 Malignancy 0 0 Skin eruptions, % Heliotrope rash
67 57 Facial erythema ** 56 100 Gottron sign 89 100 Prognosis (alive), % 100 100 * Data from .
The clinical examination of this patient showed heliotrope rash
of the eyelids and erythema on the extensor surface of the finger joints.
The heliotrope rash
is classically a prominent violaceous erythema on the eyelids; however, it's often a subtle abnormality that waxes and wanes.