HSPA14

(redirected from heat shock 70 kDa protein 14)

HSPA14

A gene on chromosome 10p13 that encodes a member of the heat shock protein 70 (HSP70) family which is a component of the ribosome-associated complex (RAC), a heterodimer composed of Hsp70/DnaK-type chaperone HSPA14 and Hsp40/DnaJ-type chaperone DNAJC2. The RAC binds to nascent polypeptides, maintaining them in a folding-competent state while DNAJC2 stimulates HSPA14’s ATPase activity.
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