heart field


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heart field

The region of the embryo destined to produce the heart.
See also: field
References in periodicals archive ?
Waldo confirmed that the second heart field progenitor cells migrate and differentiate into the a-SMA-positive smooth muscle cells of the two arteries.[22] Our data indicate that after aortopulmonary septation, the number of a-SMA-positive cells surrounding the endothelium increases gradually in the arterial wall, thus supporting smooth muscle formation in the arterial tunica media.
Black, "Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development," Development, vol.
Wallis et al., "Conotruncal myocardium arises from a secondary heart field," Development, vol.
Vertebrate hearts form from two distinct cell populations, termed first heart field and second heart field.
During cardiac development, two heart fields emerge termed the First Heart Field (FHF) and Second Heart Field (SHF).
The study of atrioventricular septation defect phenotype of Shh [sup]−/−mutant mouse embryos demonstrated that the Shh signaling is important in the septation of the mammalian heart into four chambers.[sup][2] During mouse embryonic development, EVC expressed in the secondary heart field, including both the outflow tract and the dorsal mesenchymal protrusion, and in mesenchymal structures of the atrial septum and the atrioventricular cushions.
Heart tissue forms in two distinct phases known as the First Heart Field, which includes the left ventricle and portions of both atrial chambers, and the Second Heart Field (SHF), which consists of the right ventricle and outflow tract.

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