hard drusen

hard drusen

type of exudative or typical drusen that appear ophthalmoscopically as discrete, yellow nodules characterized histopathologically by well-defined accumulations of hyaline material in the inner and outer collagenous zones of Bruch membrane.

hard dru·sen

(hahrd drū'sĕn)
Type of exudative or typical drusen that appears ophthalmoscopically as discrete, yellow nodules characterized histopathologically by well-defined accumulations of hyaline material in the inner and outer collagenous zones of the Bruch membrane
References in periodicals archive ?
According to the research, published in the journal Ophthalmic Research, the spots known as 'hard drusen' are made of fat and calcium deposit that form in a layer underneath the retina and can be seen in scans.
According to the research, published in the journal Ophthalmic Research, the spots known as "hard drusen" are made of fat and calcium deposit that form in a layer underneath the retina and can be seen in scans.
The exclusion criteria were as follows: (1) mild or moderate myopia (refractive error >-6D); (2) clinical features of age-related maculopathy such as soft or hard drusen; (3) a history of other ocular disorders or intraocular surgery, such as multifocal choroiditis or punctate inner choroidopathy, ocular trauma, severe cataract, retinal artery or retinal vein occlusion, diabetic retinopathy, or other retinal vascular diseases; and (4) previous ocular therapy, such as laser photocoagulation, photodynamic therapy, or intravitreal injection of anti-VEGF.
Although "hard drusen" can appear everywhere in the retina, they are usually located in the peripheral retina and are characterized by hemispherical structures with well-defined borders.
Hard drusen are small and distinct lesions with sharp borders (this type of drusen may not cause vision problems for a long time and is normal with aging, and most people over 40 have some hard drusen).
The exudative type of ARMD is diagnosed by the presence of subretinal fluid or hemorrhage, fluid or hemorrhage beneath the RPE, accompanied with ipsilateral detachment of RPE, hard drusen, vitreous hemorrhage, a combination of the previous elements or geographic atrophy, and subretinal fibrosis (scar) in the final stages [11].
While on the surface, exudates may be mistaken for hard drusen, OCT is able to clearly differentiate between the two based on their differences in retinal location.
AMD was defined as the presence of [greater than or equal to] 10 small ([less than or equal to] 63 [micro]m), hard drusen and pigmentary changes or at least 1 intermediate (64-124 [micro]m) or large ([greater than or equal to]125 [micro]m) drusen inside the 6 mm ETDRS grid.
While the OCT has an important and useful place in practice, P perhaps we are looking at this the wrong way round in that with the OCT we can see changes in the macula; hard drusen, etc, but only after the changes have occurred.
At this stage they usually have well defined edges (hard drusen) and are often bilaterally scattered at the posterior pole.
Hard drusen are small, punctate yellow dots, which can be found in the macular region but also throughout the retina.