haptenization

haptenization (hap·te·nī·zāˑ·shn),

n the combination of an antigenic compound with a carrier protein molecule, intended to achieve a high enough molecular weight to stimulate an immune response.
References in periodicals archive ?
Briefly, sensitization involves skin penetration of the sensitizing agent with a subsequent haptenization of endogenous proteins.
This process is named haptenization and the sensitizing chemistry is termed hapten.
Her particular hepatic metabolism further increased the drugs' concentration, favoring the haptenization of liver proteins, eventually leading to the development of an autoimmune hepatitis.
However, haptenization reaction does not occur directly for most drugs.