haplotype


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haplotype

 [hap´lo-tīp]
1. a set of alleles of a group of closely linked genes, such as the HLA complex, which are usually inherited as a unit, an individual inheriting a complete haplotype from each parent.
2. the genetic constitution of an individual at a set of linked genes.

hap·lo·type

(hap'lō-tīp),
1. The genetic constitution of an individual with respect to one member of a pair of allelic genes; individuals are of the same haplotype (but of different genotypes) if alike with respect to one allele of a pair but different with respect to the other allele of a pair.
2. In immunogenetics, that portion of the phenotype determined by a set of closely linked genes inherited from one parent (that is, genes located on one of the pair of chromosomes).
[haplo- + G. typos, impression, model]

haplotype

(hăp′lə-tīp′)
n.
A set of alleles of different genes that are closely linked on one chromosome and are usually inherited as a unit.

hap·lo·type

(hap'lō-tīp)
1. The genetic constitution of an individual with respect to one member of a pair of allelic genes; individuals are of the same haplotype (but of different genotypes) if alike with respect to one allele of a pair but different with respect to the other allele of a pair.
2. immunogenetics That portion of the phenotype determined by a set of closely linked genes inherited from one parent (i.e., genes located on one of the pair of chromosomes). The human major histocompatability complex comprises 4 recognized loci (A, B, C, and D) for which there are more than 50 alleles. Similarly, the allotypic markers (antigens) of the immunoglobulin subclasses IgG1, IgG2, IgG3, and IgA2 occur in combinations and are inherited as units almost always unchanged in transmission; the alleles that control these various haploptypes are not linked to those controlling the antigens of the κ type L chains.
[haplo- + G. typos, impression, model]

haplotype

The entire set of allelic variants that may be found at any particular genetic location.

haplotype

see HLA SYSTEM.

Haplotype

A set of alleles (an alternative form of a gene that can occupy a particular place on a chromosome) of a group of closely linked genes which are usually inherited as a unit.
References in periodicals archive ?
In addition, two D-Loop haplotype clusters, according phylogenetic network from Kxy, were identified from the 252 Tongren frogs.
They first showed that they could identify centromeric haplotypes, or "cenhaps," in Drosophila fruit flies.
Twenty-seven polymorphism sites were observed within the Agu population, demonstrating five different haplotypes (type 1-type 5).
In addition to significant differences in cytb haplotype frequencies among the four sampled locations, the spatial distribution of the 14 haplotypes suggests that there is somewhat restricted gene flow between sites.
Results from their hair samples revealed two different haplotypes. One was already known in Wales, but the other was unique.
We considered 2 haplotypes the same only when all 9 markers shared the same allelic variant.
The mean in PDCRS frontosubcortical scores changed by 1.80 points in MAPT H1/H1 haplotype and by 1.58 points other haplotypes.
The main thrust of our study has been the ability to estimate, with high confidence, haplotype frequencies from mixed resolution typings including MAC (https://hml.
Identical sequences were considered as the same haplotype. Nucleotide sequences of D-loop gene of mtDNA from Central Javanese duck in this research together with other Anas isolates from Genbank were aligned with ClustalW of MEGA-6.06 program (Kumar, Tamura, Jakobsen, & Nei, 2001).
Of the 58 samples from which Red Fox mtDNA was successfully extracted, 46 (79%) were of the cytochrome b/D-loop haplotype combination A-19 (Table 1), the most common haplotype in native populations from the Rocky Mountains, Sierra Nevada, and the Cascade Range of Oregon (Aubry and others 2009).