haplo-compatible

haplo-compatible

(hap′lō-kŏm-pat′ĭ-bĕl) [Gr. haploos, simple, single + compatible]
Having half of the same human leukocyte antigens (HLA-antigens) as another person. Typically a parent is haplo-compatible with each of his or her children, because each child inherits half of its HLA genes from each parent. In immunology and transplant medicine, this means that a parent and child are only halfmatched with respect to these crucial tissue markers. When a haplo-compatible donor gives an organ, e.g., bone marrow, to his or her child, T lymphocytes must be removed from the donated marrow to limit the risk of graft-versus-host disease.