hantavirus pulmonary syndrome

hantavirus pulmonary syndrome

a febrile disease caused by several species of Hantavirus (Andes, Bayou, Black Creek Canal, New York, and Sin Nombre viruses) in North and South America and characterized by thrombocytopenia, leukocytosis, and capillary leakage in the lungs, with death due to shock and cardiac complications.

Farlex Partner Medical Dictionary © Farlex 2012

An often fatal respiratory tract infection with massive acute pulmonary edema often at death caused by a hantavirus; the first cluster occurred in the Four Corners region of Southwestern US
Epidemiology Mean age 32, 61% women, 72% Native American
Case definition Unexplained bilateral interstitial infiltrates on chest films, arterial O2 saturation < 90%
Prodrome Fever, myalgia (100%), cough or shortness of breath (75%), GI symptoms, headache, tachycardia, tachypnea, hypotension
Lab Leukocytosis—± 26 x 109/L—often with myeloid precursors, increased haematocrit, thrombocytopaenia of ±64 x 109/L, increased PT, increased aPTT, increased LD, decreased serum protein, proteinuria
Prevention Vaccine is being developed

Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

hantavirus pulmonary syndrome

An often fatal RTI caused by a hantavirus; the first cluster occurred in the Four Corners region of Southwestern US Epidemiology Mean age 32, 61% ♀, 72% Native American Case definition Unexplained bilateral interstitial infiltrates on chest film, arterial O₂ saturation < 90% Prodrome Fever, myalgia-100%, cough or SOB-76%, GI Sx, headache, tachycardia, tachypnea, hypotension Lab Leukocytosis–± 26 x 109/L, often with myeloid precursors, ↑ Hct, thrombocytopenia of ±64 x 109/L, ↑ PT, ↑ aPTT, ↑ LD, ↓ serum protein, proteinuria Diagnosis Immunohistochemistry, Western blot, ELISA, IgM capture ELISA; massive acute pulmonary edema is common at death

McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

Han·ta·vi·rus pul·mo·na·ry syn·drome

(hahn'tă-vī'rŭs pul'mŏ-nar-ē sin'drōm)

A febrile disease caused by several species of Hantavirus (Andes, Bayou, Black Creek Canal, New York, and Sin Nombre viruses) in North and South America and characterized by thrombocytopenia, leukocytosis, and capillary leakage in the lungs, with death due to shock and cardiac complications.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

hantavirus pulmonary syndrome

Acute respiratory illness featuring a brief period of fever, muscle pains, headache, nausea and cough followed by severe shock and pulmonary oedema simulating the acute adult RESPIRATORY DISTRESS SYNDROME (ARDS). The mortality without specific treatment is 50–75 per cent but the drug ribavirin is effective. The disease is caused by a strain of hanta virus and was originally though to be acquired only from rodents. Human case-to-case infection has now been demonstrated.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005