Tuberculosis cutis verrucosa, pyoderma gangrenosum, halogenoderma
, squamous cell carcinoma and sweet syndrome are the other less reported clinical entities that should be considered in cases with similar lesions.
Other entities with exuberant pseudoepitheliomatous hyperplasia not typically considered interface processes may rarely enter the differential, including deep fungal infections, the halogenodermas (bromoderma, iododerma), and some perforating disorders.
The halogenodermas are a group of dermatoses caused by chronic application or ingestion of halogens.
PEH with neutrophilic microabscesses is typically seen in halogenodermas
, infections like chromomycosis and blastomycosis, granuloma inguinale, leishmaniasis, and pemphigus vegetans .
Inflammation in scarring disorders, burns, ischemia, reactions to cryosurgery, and other mechanical injuries, (14,17,18) halogenodermas
, (19) reactions to arthropod bites, (20) and nutritional diseases of the skin (13) can cause this pseudoneoplastic condition.