haemosiderin


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Related to haemosiderin: hemosiderosis

haemosiderin

An iron-storing complex primarily composed of ferritin, present in highest concentrations in macrophages, which accumulates in response to haemorrhage. The term is included here to flag the differences in pronunciation.
 
Medspeak-UK—HEY mow sih dur inn.
 
Medspeak-US—HE mow sih dur inn.

he·mo·sid·er·in

(hē'mō-sid'ĕr-in)
A yellow or brown protein produced by phagocytic digestion of hematin; found in most tissues, but especially in the liver; at higher levels, it stains blue with Perls Prussian blue stain.
Synonym(s): haemosiderin.
[hemo- + G. sidēros, iron, + -in]

haemosiderin

One of the two forms in which iron is stored in the body. The bulk of the iron is stored as haemosiderin. See also FERRITIN.

he·mo·sid·er·in

(hē'mō-sid'ĕr-in)
A yellow or brown protein produced by phagocytic digestion of hematin; found in most tissues, but especially in the liver.
Synonym(s): haemosiderin.
[hemo- + G. sidēros, iron, + -in]
References in periodicals archive ?
Serum ferritin in healthy Danes: relation to marrow haemosiderin iron stores.
Interstitial haemosiderin in the lungs of sudden infant death syndrome: a histological hallmark of 'near-miss' episodes?
The underlying stroma showed sheets of haemosiderin laden macrophages and clusters of mucus glands.
The remainder is storage iron ferritin (4-8 mg/kg), haemosiderin (2-4 mg/kg) and iron bound to transferrin (<1 mg/kg).
Two (4%) of these patients had a definite history of trauma but histopathologically did not reveal any extravasated RBC's, fibrin thrombi or haemosiderin laden macrophages.
A low intensity signal on MRI may be found in only few cases all on sequences due to haemosiderin deposits.
For example, ferrous or ferric iron shortens T1 and T2 signal, methaemoglobin causes an increased T1 signal and variable T2 signal whereas haemosiderin decreases T1 and T2 signal.
(2) It is suggested that lymphatic and venous obstruction, protein-rich interstitial fluid, tissue haemosiderin and subcutaneous infection contribute to the evolution and perpetuation of chronic lymphoedema.
Iron is also stored in an insoluble form in a poorly defined storage protein, haemosiderin, presumed to be derived from the lysosomal degradation of ferritin.
Also, KS lesions that have completely responded to therapy sometimes remain as hyperpigmented areas, presumably from haemosiderin deposits.
1), haemosiderin pigment, plasma cells and hyaline globules.
* Thrombosed Berry aneurysm: often will have calcified rim, and haemosiderin staining on gradient echo/ SWI sequences.