haemosiderin

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Related to haemosiderin: hemosiderosis

haemosiderin

An iron-storing complex primarily composed of ferritin, present in highest concentrations in macrophages, which accumulates in response to haemorrhage. The term is included here to flag the differences in pronunciation.

Medspeak-UK—HEY mow sih dur inn.

Medspeak-US—HE mow sih dur inn.

he·mo·sid·er·in

(hē'mō-sid'ĕr-in)

A yellow or brown protein produced by phagocytic digestion of hematin; found in most tissues, but especially in the liver; at higher levels, it stains blue with Perls Prussian blue stain.
Synonym(s): haemosiderin.

[hemo- + G. sidēros, iron, + -in]

haemosiderin

One of the two forms in which iron is stored in the body. The bulk of the iron is stored as haemosiderin. See also FERRITIN.

he·mo·sid·er·in

(hē'mō-sid'ĕr-in)

A yellow or brown protein produced by phagocytic digestion of hematin; found in most tissues, but especially in the liver.
Synonym(s): haemosiderin.

[hemo- + G. sidēros, iron, + -in]

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References in periodicals archive ?

Serum ferritin in healthy Danes: relation to marrow haemosiderin iron stores.

Deficiencia de hierro en donantes de sangre

Interstitial haemosiderin in the lungs of sudden infant death syndrome: a histological hallmark of 'near-miss' episodes?

Update: pulmonary hemorrhage/hemosiderosis among infants - Cleveland, Ohio, 1993-1996

The underlying stroma showed sheets of haemosiderin laden macrophages and clusters of mucus glands.

Enteric cyst in the left posterior mediastinum mimicking a hydatid cyst on chest Computed Tomography scan

The remainder is storage iron ferritin (4-8 mg/kg), haemosiderin (2-4 mg/kg) and iron bound to transferrin (<1 mg/kg).

Iron deficiency in children

Two (4%) of these patients had a definite history of trauma but histopathologically did not reveal any extravasated RBC's, fibrin thrombi or haemosiderin laden macrophages.

Role of needle synovial biopsy in joint diseases

A low intensity signal on MRI may be found in only few cases all on sequences due to haemosiderin deposits.

Laparoscopic partial splenectomy for littoral cell angioma

For example, ferrous or ferric iron shortens T1 and T2 signal, methaemoglobin causes an increased T1 signal and variable T2 signal whereas haemosiderin decreases T1 and T2 signal.

Extramedullary haematopoiesis causing spinal cord compression

(2) It is suggested that lymphatic and venous obstruction, protein-rich interstitial fluid, tissue haemosiderin and subcutaneous infection contribute to the evolution and perpetuation of chronic lymphoedema.

Kaposi's sarcoma, lymphoedema and gangrene in AIDS--a therapeutic challenge

Iron is also stored in an insoluble form in a poorly defined storage protein, haemosiderin, presumed to be derived from the lysosomal degradation of ferritin.

Iron transport & homeostasis mechanisms: their role in health & disease

Also, KS lesions that have completely responded to therapy sometimes remain as hyperpigmented areas, presumably from haemosiderin deposits.

Imaging techniques for Kaposi's sarcoma

1), haemosiderin pigment, plasma cells and hyaline globules.

Kaposi's sarcoma, a south African perspective: demographic and pathological features

* Thrombosed Berry aneurysm: often will have calcified rim, and haemosiderin staining on gradient echo/ SWI sequences.